Endophthalmitis associated with intravitreal injections: Office-based setting and operating room setting

Homayoun Tabandeh, Francesco Boscia, Alessandra Sborgia, Lorenza Ciracì, Pouya Dayani, Cesare Mariotti, Claudio Furino, Harry W. Flynn

Research output: Contribution to journalArticle

45 Scopus citations

Abstract

Purpose: To report on the occurrence of endophthalmitis after intravitreal injections (IVI) in two different settings: office-based and operating room. Methods: Consecutive case series. Retrospective review of all patients who underwent IVI by 2 physicians between January 2009 and December 2011. Group A underwent IVI in the examination room in office-based setting and Group B underwent IVI in the operating room. Results: A total of 11,710 IVIs were performed during the study period. Group A: A total of 8,647 IVIs performed including 2,041 ranibizumab, 6,169 bevacizumab, and 437 triamcinolone acetonide. The diagnosis included neovascular age-related macular degeneration (5,376), diabetic macular edema (1,587), retinal vein occlusion (1,068), and miscellaneous diagnosis (616). Group B: A total of 3,063 IVIs performed including 683 ranibizumab, 2,364 bevacizumab, and 16 triamcinolone acetonide. The diagnosis included neovascular age-related macular degeneration (1,836), diabetic macular edema (771), retinal vein occlusion (189), and miscellaneous diagnosis (267). A total of 5 cases (0.043%) of clinically suspected endophthalmitis occurred in 11,710 injections. Three cases (0.035%) occurred in Group A, and 2 cases (0.065%) occurred in Group B. Conclusion: The rate of clinically suspected endophthalmitis after IVIs is low whether the procedure is performed in the office or operating room setting. The findings have implications in terms of the patient convenience, efficiency, and cost of administrating these treatments.

Original languageEnglish (US)
Pages (from-to)18-23
Number of pages6
JournalRetina
Volume34
Issue number1
DOIs
StatePublished - Jan 1 2014

Keywords

  • Age-related macular degeneration
  • Bevacizumab
  • Diabetic retinopathy
  • Endophthalmitis
  • Intravitreal injection
  • Macular edema
  • Ranibizumab
  • Retinal vein occlusion
  • Triamcinolone

ASJC Scopus subject areas

  • Ophthalmology

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  • Cite this

    Tabandeh, H., Boscia, F., Sborgia, A., Ciracì, L., Dayani, P., Mariotti, C., Furino, C., & Flynn, H. W. (2014). Endophthalmitis associated with intravitreal injections: Office-based setting and operating room setting. Retina, 34(1), 18-23. https://doi.org/10.1097/IAE.0000000000000008