Endophthalmitis after pars plana vitrectomy

S. M. Cohen, Harry W Flynn, T. G. Murray, William E Smiddy, L. R. Avins, C. F. Blodi, S. Chang, S. M. Cohen, S. G. Elner, H. W. Flynn, W. S. Grizzard, M. E. Hammer, D. P. Han, M. W. Johnson, W. F. Mieler, T. G. Murray, A. J. Packer, V. S. Reppucci, W. E. Smiddy, T. A. Weingeist

Research output: Contribution to journalArticle

106 Citations (Scopus)

Abstract

Purpose: To describe the clinical course and incidence of culture-proven postvitrectomy endophthalmitis in 18 patients from five academic centers and three private practices. Methods: Patients undergoing pars plane vitrectomy for recent trauma or endophthalmitis were excluded. The average age was 58 years (range, 21-85 year). Sixty-one percent of the patients (11/18) had diabetes mellitus. The indication for initial vitrectomy was vitreous hemorrhage (n = 10), macular epiretinal membrane (n = 3), recurrent retinal detachment with proliferative vitreoretinopathy (n = 2), retinal detachment with retinoschisis (n = 1), proliferative diabetic retinopathy with tractional retinal detachment (n = 1), and dislocated intraocular lens (n = 1). None of these eyes received prophylactic intraocular antibiotics during the vitrectomy. Results: All eyes were treated with intraocular antibiotics after the diagnosis of postvitrectomy endophthalmitis was made. Final visual acuity ranged from 20/20 to no light perception and included five eyes with 20/50 or better visual acuity and 11 eyes with less than 5/200 visual acuity. Nine eyes had a final visual acuity of no light perception. Of the 16 eyes infected with a single organism, 71% (5/7) of eyes infected with coagulase- negative staphylococci retained 20/50 or better final visual acuity compared with no eyes (0/9) infected with other organisms (P = 0.005). Two eyes infected with both coagulase-negative Staphylococcus and Streptococcus had a final visual acuity of 20/400. Three eyes with a total hypopyon later had enucleation or evisceration. Based on the data from four medical centers, the incidence of endophthalmitis after pars plana vitrectomy performed over the last 10 years was 9/12,216 (0.07%). Conclusion: Endophthalmitis after vitrectomy is rare. Postvitrectomy bacterial endophthalmitis caused by organisms other than coagulase-negative staphylococci has a poor visual prognosis.

Original languageEnglish
Pages (from-to)705-712
Number of pages8
JournalOphthalmology
Volume102
Issue number5
StatePublished - Jan 1 1995

Fingerprint

Endophthalmitis
Temazepam
Vitrectomy
Visual Acuity
Coagulase
Retinal Detachment
Staphylococcus
Retinoschisis
Epiretinal Membrane
Anti-Bacterial Agents
Proliferative Vitreoretinopathy
Vitreous Hemorrhage
Light
Intraocular Lenses
Private Practice
Incidence
Diabetic Retinopathy
Streptococcus
Diabetes Mellitus

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Cohen, S. M., Flynn, H. W., Murray, T. G., Smiddy, W. E., Avins, L. R., Blodi, C. F., ... Weingeist, T. A. (1995). Endophthalmitis after pars plana vitrectomy. Ophthalmology, 102(5), 705-712.

Endophthalmitis after pars plana vitrectomy. / Cohen, S. M.; Flynn, Harry W; Murray, T. G.; Smiddy, William E; Avins, L. R.; Blodi, C. F.; Chang, S.; Cohen, S. M.; Elner, S. G.; Flynn, H. W.; Grizzard, W. S.; Hammer, M. E.; Han, D. P.; Johnson, M. W.; Mieler, W. F.; Murray, T. G.; Packer, A. J.; Reppucci, V. S.; Smiddy, W. E.; Weingeist, T. A.

In: Ophthalmology, Vol. 102, No. 5, 01.01.1995, p. 705-712.

Research output: Contribution to journalArticle

Cohen, SM, Flynn, HW, Murray, TG, Smiddy, WE, Avins, LR, Blodi, CF, Chang, S, Cohen, SM, Elner, SG, Flynn, HW, Grizzard, WS, Hammer, ME, Han, DP, Johnson, MW, Mieler, WF, Murray, TG, Packer, AJ, Reppucci, VS, Smiddy, WE & Weingeist, TA 1995, 'Endophthalmitis after pars plana vitrectomy', Ophthalmology, vol. 102, no. 5, pp. 705-712.
Cohen SM, Flynn HW, Murray TG, Smiddy WE, Avins LR, Blodi CF et al. Endophthalmitis after pars plana vitrectomy. Ophthalmology. 1995 Jan 1;102(5):705-712.
Cohen, S. M. ; Flynn, Harry W ; Murray, T. G. ; Smiddy, William E ; Avins, L. R. ; Blodi, C. F. ; Chang, S. ; Cohen, S. M. ; Elner, S. G. ; Flynn, H. W. ; Grizzard, W. S. ; Hammer, M. E. ; Han, D. P. ; Johnson, M. W. ; Mieler, W. F. ; Murray, T. G. ; Packer, A. J. ; Reppucci, V. S. ; Smiddy, W. E. ; Weingeist, T. A. / Endophthalmitis after pars plana vitrectomy. In: Ophthalmology. 1995 ; Vol. 102, No. 5. pp. 705-712.
@article{0ba3db13151443b0910c0def4a0bd3b5,
title = "Endophthalmitis after pars plana vitrectomy",
abstract = "Purpose: To describe the clinical course and incidence of culture-proven postvitrectomy endophthalmitis in 18 patients from five academic centers and three private practices. Methods: Patients undergoing pars plane vitrectomy for recent trauma or endophthalmitis were excluded. The average age was 58 years (range, 21-85 year). Sixty-one percent of the patients (11/18) had diabetes mellitus. The indication for initial vitrectomy was vitreous hemorrhage (n = 10), macular epiretinal membrane (n = 3), recurrent retinal detachment with proliferative vitreoretinopathy (n = 2), retinal detachment with retinoschisis (n = 1), proliferative diabetic retinopathy with tractional retinal detachment (n = 1), and dislocated intraocular lens (n = 1). None of these eyes received prophylactic intraocular antibiotics during the vitrectomy. Results: All eyes were treated with intraocular antibiotics after the diagnosis of postvitrectomy endophthalmitis was made. Final visual acuity ranged from 20/20 to no light perception and included five eyes with 20/50 or better visual acuity and 11 eyes with less than 5/200 visual acuity. Nine eyes had a final visual acuity of no light perception. Of the 16 eyes infected with a single organism, 71{\%} (5/7) of eyes infected with coagulase- negative staphylococci retained 20/50 or better final visual acuity compared with no eyes (0/9) infected with other organisms (P = 0.005). Two eyes infected with both coagulase-negative Staphylococcus and Streptococcus had a final visual acuity of 20/400. Three eyes with a total hypopyon later had enucleation or evisceration. Based on the data from four medical centers, the incidence of endophthalmitis after pars plana vitrectomy performed over the last 10 years was 9/12,216 (0.07{\%}). Conclusion: Endophthalmitis after vitrectomy is rare. Postvitrectomy bacterial endophthalmitis caused by organisms other than coagulase-negative staphylococci has a poor visual prognosis.",
author = "Cohen, {S. M.} and Flynn, {Harry W} and Murray, {T. G.} and Smiddy, {William E} and Avins, {L. R.} and Blodi, {C. F.} and S. Chang and Cohen, {S. M.} and Elner, {S. G.} and Flynn, {H. W.} and Grizzard, {W. S.} and Hammer, {M. E.} and Han, {D. P.} and Johnson, {M. W.} and Mieler, {W. F.} and Murray, {T. G.} and Packer, {A. J.} and Reppucci, {V. S.} and Smiddy, {W. E.} and Weingeist, {T. A.}",
year = "1995",
month = "1",
day = "1",
language = "English",
volume = "102",
pages = "705--712",
journal = "Ophthalmology",
issn = "0161-6420",
publisher = "Elsevier Inc.",
number = "5",

}

TY - JOUR

T1 - Endophthalmitis after pars plana vitrectomy

AU - Cohen, S. M.

AU - Flynn, Harry W

AU - Murray, T. G.

AU - Smiddy, William E

AU - Avins, L. R.

AU - Blodi, C. F.

AU - Chang, S.

AU - Cohen, S. M.

AU - Elner, S. G.

AU - Flynn, H. W.

AU - Grizzard, W. S.

AU - Hammer, M. E.

AU - Han, D. P.

AU - Johnson, M. W.

AU - Mieler, W. F.

AU - Murray, T. G.

AU - Packer, A. J.

AU - Reppucci, V. S.

AU - Smiddy, W. E.

AU - Weingeist, T. A.

PY - 1995/1/1

Y1 - 1995/1/1

N2 - Purpose: To describe the clinical course and incidence of culture-proven postvitrectomy endophthalmitis in 18 patients from five academic centers and three private practices. Methods: Patients undergoing pars plane vitrectomy for recent trauma or endophthalmitis were excluded. The average age was 58 years (range, 21-85 year). Sixty-one percent of the patients (11/18) had diabetes mellitus. The indication for initial vitrectomy was vitreous hemorrhage (n = 10), macular epiretinal membrane (n = 3), recurrent retinal detachment with proliferative vitreoretinopathy (n = 2), retinal detachment with retinoschisis (n = 1), proliferative diabetic retinopathy with tractional retinal detachment (n = 1), and dislocated intraocular lens (n = 1). None of these eyes received prophylactic intraocular antibiotics during the vitrectomy. Results: All eyes were treated with intraocular antibiotics after the diagnosis of postvitrectomy endophthalmitis was made. Final visual acuity ranged from 20/20 to no light perception and included five eyes with 20/50 or better visual acuity and 11 eyes with less than 5/200 visual acuity. Nine eyes had a final visual acuity of no light perception. Of the 16 eyes infected with a single organism, 71% (5/7) of eyes infected with coagulase- negative staphylococci retained 20/50 or better final visual acuity compared with no eyes (0/9) infected with other organisms (P = 0.005). Two eyes infected with both coagulase-negative Staphylococcus and Streptococcus had a final visual acuity of 20/400. Three eyes with a total hypopyon later had enucleation or evisceration. Based on the data from four medical centers, the incidence of endophthalmitis after pars plana vitrectomy performed over the last 10 years was 9/12,216 (0.07%). Conclusion: Endophthalmitis after vitrectomy is rare. Postvitrectomy bacterial endophthalmitis caused by organisms other than coagulase-negative staphylococci has a poor visual prognosis.

AB - Purpose: To describe the clinical course and incidence of culture-proven postvitrectomy endophthalmitis in 18 patients from five academic centers and three private practices. Methods: Patients undergoing pars plane vitrectomy for recent trauma or endophthalmitis were excluded. The average age was 58 years (range, 21-85 year). Sixty-one percent of the patients (11/18) had diabetes mellitus. The indication for initial vitrectomy was vitreous hemorrhage (n = 10), macular epiretinal membrane (n = 3), recurrent retinal detachment with proliferative vitreoretinopathy (n = 2), retinal detachment with retinoschisis (n = 1), proliferative diabetic retinopathy with tractional retinal detachment (n = 1), and dislocated intraocular lens (n = 1). None of these eyes received prophylactic intraocular antibiotics during the vitrectomy. Results: All eyes were treated with intraocular antibiotics after the diagnosis of postvitrectomy endophthalmitis was made. Final visual acuity ranged from 20/20 to no light perception and included five eyes with 20/50 or better visual acuity and 11 eyes with less than 5/200 visual acuity. Nine eyes had a final visual acuity of no light perception. Of the 16 eyes infected with a single organism, 71% (5/7) of eyes infected with coagulase- negative staphylococci retained 20/50 or better final visual acuity compared with no eyes (0/9) infected with other organisms (P = 0.005). Two eyes infected with both coagulase-negative Staphylococcus and Streptococcus had a final visual acuity of 20/400. Three eyes with a total hypopyon later had enucleation or evisceration. Based on the data from four medical centers, the incidence of endophthalmitis after pars plana vitrectomy performed over the last 10 years was 9/12,216 (0.07%). Conclusion: Endophthalmitis after vitrectomy is rare. Postvitrectomy bacterial endophthalmitis caused by organisms other than coagulase-negative staphylococci has a poor visual prognosis.

UR - http://www.scopus.com/inward/record.url?scp=0028997327&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028997327&partnerID=8YFLogxK

M3 - Article

C2 - 7777268

AN - SCOPUS:0028997327

VL - 102

SP - 705

EP - 712

JO - Ophthalmology

JF - Ophthalmology

SN - 0161-6420

IS - 5

ER -