Endophthalmitis after intravitreal injections is a rare but devastating complication of this common eye procedure. Patients typically present within 5 days of their injection with decreased vision, pain, and redness. However, the absence of any one of these in the presence of other symptoms should not exclude the diagnosis of endophthalmitis. Treatment consists of obtaining a vitreous sample and administering intravitreal antibiotics. Vitrectomy may be indicated in some cases. Preventive measures include the use of a lid speculum and topical povidone-iodine during the procedure, and clinicians may consider the use of masks or having all participants refrain from speaking.
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