Endogenous Pseudallescheria boydii endophthalmitis in a patient with ring-enhancing brain lesions

K. K M Luu, I. U. Scott, Darlene Miller, Janet L Davis

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

A 46-year-old man, status post liver transplantation and taking immunosuppressive medications, was admitted after suffering a generalized seizure. Magnetic resonance imaging of the brain revealed two ring-enhancing lesions and treatment was begun for presumed toxoplasmic encephalitis. He was already receiving amphotericin B for a skin lesion suspected to be caused by candidiasis. One day after the seizure, he complained of photophobia in the left eye. Intraocular inflammation and a small infiltrate in the macula were seen. Vision deteriorated over the next three days. Vitreous tap and injection of amphotericin B and vancomycin were performed, but the intraocular inflammation continued to increase. On day 15, a vitrectomy was performed. The vitreous specimen ultimately grew Pseudallescheria boydii. The patient died on hospital day 30 from complications of the brain abscesses. Pseudallescheria boydii should be considered in the differential diagnosis of endophthalmitis, especially in patients with immunosuppression, serious medical disease, or ring-enhancing brain lesions.

Original languageEnglish
Pages (from-to)325-329
Number of pages5
JournalOphthalmic Surgery and Lasers
Volume32
Issue number4
StatePublished - Jul 28 2001

Fingerprint

Pseudallescheria
Endophthalmitis
Amphotericin B
Seizures
Inflammation
Photophobia
Brain Abscess
Candidiasis
Vitrectomy
Brain
Encephalitis
Vancomycin
Immunosuppressive Agents
Liver Transplantation
Immunosuppression
Differential Diagnosis
Magnetic Resonance Imaging
Skin
Injections
Therapeutics

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Endogenous Pseudallescheria boydii endophthalmitis in a patient with ring-enhancing brain lesions. / Luu, K. K M; Scott, I. U.; Miller, Darlene; Davis, Janet L.

In: Ophthalmic Surgery and Lasers, Vol. 32, No. 4, 28.07.2001, p. 325-329.

Research output: Contribution to journalArticle

@article{d7c888fb64bd471b8983fc76c2b259a9,
title = "Endogenous Pseudallescheria boydii endophthalmitis in a patient with ring-enhancing brain lesions",
abstract = "A 46-year-old man, status post liver transplantation and taking immunosuppressive medications, was admitted after suffering a generalized seizure. Magnetic resonance imaging of the brain revealed two ring-enhancing lesions and treatment was begun for presumed toxoplasmic encephalitis. He was already receiving amphotericin B for a skin lesion suspected to be caused by candidiasis. One day after the seizure, he complained of photophobia in the left eye. Intraocular inflammation and a small infiltrate in the macula were seen. Vision deteriorated over the next three days. Vitreous tap and injection of amphotericin B and vancomycin were performed, but the intraocular inflammation continued to increase. On day 15, a vitrectomy was performed. The vitreous specimen ultimately grew Pseudallescheria boydii. The patient died on hospital day 30 from complications of the brain abscesses. Pseudallescheria boydii should be considered in the differential diagnosis of endophthalmitis, especially in patients with immunosuppression, serious medical disease, or ring-enhancing brain lesions.",
author = "Luu, {K. K M} and Scott, {I. U.} and Darlene Miller and Davis, {Janet L}",
year = "2001",
month = "7",
day = "28",
language = "English",
volume = "32",
pages = "325--329",
journal = "Ophthalmic Surgery Lasers and Imaging Retina",
issn = "2325-8160",
publisher = "Slack Incorporated",
number = "4",

}

TY - JOUR

T1 - Endogenous Pseudallescheria boydii endophthalmitis in a patient with ring-enhancing brain lesions

AU - Luu, K. K M

AU - Scott, I. U.

AU - Miller, Darlene

AU - Davis, Janet L

PY - 2001/7/28

Y1 - 2001/7/28

N2 - A 46-year-old man, status post liver transplantation and taking immunosuppressive medications, was admitted after suffering a generalized seizure. Magnetic resonance imaging of the brain revealed two ring-enhancing lesions and treatment was begun for presumed toxoplasmic encephalitis. He was already receiving amphotericin B for a skin lesion suspected to be caused by candidiasis. One day after the seizure, he complained of photophobia in the left eye. Intraocular inflammation and a small infiltrate in the macula were seen. Vision deteriorated over the next three days. Vitreous tap and injection of amphotericin B and vancomycin were performed, but the intraocular inflammation continued to increase. On day 15, a vitrectomy was performed. The vitreous specimen ultimately grew Pseudallescheria boydii. The patient died on hospital day 30 from complications of the brain abscesses. Pseudallescheria boydii should be considered in the differential diagnosis of endophthalmitis, especially in patients with immunosuppression, serious medical disease, or ring-enhancing brain lesions.

AB - A 46-year-old man, status post liver transplantation and taking immunosuppressive medications, was admitted after suffering a generalized seizure. Magnetic resonance imaging of the brain revealed two ring-enhancing lesions and treatment was begun for presumed toxoplasmic encephalitis. He was already receiving amphotericin B for a skin lesion suspected to be caused by candidiasis. One day after the seizure, he complained of photophobia in the left eye. Intraocular inflammation and a small infiltrate in the macula were seen. Vision deteriorated over the next three days. Vitreous tap and injection of amphotericin B and vancomycin were performed, but the intraocular inflammation continued to increase. On day 15, a vitrectomy was performed. The vitreous specimen ultimately grew Pseudallescheria boydii. The patient died on hospital day 30 from complications of the brain abscesses. Pseudallescheria boydii should be considered in the differential diagnosis of endophthalmitis, especially in patients with immunosuppression, serious medical disease, or ring-enhancing brain lesions.

UR - http://www.scopus.com/inward/record.url?scp=0034960180&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034960180&partnerID=8YFLogxK

M3 - Article

C2 - 11475400

AN - SCOPUS:0034960180

VL - 32

SP - 325

EP - 329

JO - Ophthalmic Surgery Lasers and Imaging Retina

JF - Ophthalmic Surgery Lasers and Imaging Retina

SN - 2325-8160

IS - 4

ER -