Endocarditis associated with antineutrophil cytoplasmic antibodies: A case report and review of the literature

Julio A. Chirinos, Vicente F. Corrales-Medina, Santiago Garcia, Daniel Lichtstein, Alan L. Bisno, Simon Chakko

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

We report a case of subacute bacterial endocarditis associated with small vessel vasculitis and a strongly positive cytoplasmic antineutrophil cytoplasmic antibody (c-ANCA) test. It is important to recognize this cause of positive c-ANCA because infectious endocarditis may closely mimic the clinical manifestations of ANCA-associated vasculitides such as Wegener granulomatosis or microscopic polyangiitis. Furthermore, ANCA-associated vasculitis may result in noninfectious endocarditis, which may be confused with bacterial endocarditis. In this paper, we review reported cases of ANCA-positive bacterial endocarditis and compare them to the reported cases of ANCA-associated idiopathic vasculitis with endocardial compromise.

Original languageEnglish
Pages (from-to)590-595
Number of pages6
JournalClinical Rheumatology
Volume26
Issue number4
DOIs
StatePublished - Apr 1 2007

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Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Antineutrophil Cytoplasmic Antibodies
Endocarditis
Bacterial Endocarditis
Microscopic Polyangiitis
Subacute Bacterial Endocarditis
Granulomatosis with Polyangiitis
Vasculitis

Keywords

  • Antineutrophil cytoplasmic antibodies
  • Endocarditis
  • Wegener granulomatosis

ASJC Scopus subject areas

  • Rheumatology
  • Immunology

Cite this

Endocarditis associated with antineutrophil cytoplasmic antibodies : A case report and review of the literature. / Chirinos, Julio A.; Corrales-Medina, Vicente F.; Garcia, Santiago; Lichtstein, Daniel; Bisno, Alan L.; Chakko, Simon.

In: Clinical Rheumatology, Vol. 26, No. 4, 01.04.2007, p. 590-595.

Research output: Contribution to journalArticle

Chirinos, Julio A. ; Corrales-Medina, Vicente F. ; Garcia, Santiago ; Lichtstein, Daniel ; Bisno, Alan L. ; Chakko, Simon. / Endocarditis associated with antineutrophil cytoplasmic antibodies : A case report and review of the literature. In: Clinical Rheumatology. 2007 ; Vol. 26, No. 4. pp. 590-595.
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