Enantioselective photoreduction of arylalkyl ketones via restricting the reaction to chirally modified zeolite cages

J. Shailaja, Keith J. Ponchot, Vaidhyanathan Ramamurthy

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

(equation presented) Obtaining a high enantiomeric excess during a photoreaction within a zeolite is hampered by the statistical distribution of reactant and chiral inductor molecules within the cages of a zeolite. By restricting the photoreactions to only those cages that contain both the reactant and a chiral inductor, one should be able to avoid reactions that yield racemic products. This approach is illustrated with the photoreduction of an arylalkyl ketone by a chiral inductor with an amino group.

Original languageEnglish
Pages (from-to)937-940
Number of pages4
JournalOrganic Letters
Volume2
Issue number7
StatePublished - Apr 6 2000
Externally publishedYes

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Zeolites
inductors
Ketones
ketones
photochemical reactions
Statistical Distributions
statistical distributions
Molecules
products
molecules

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Enantioselective photoreduction of arylalkyl ketones via restricting the reaction to chirally modified zeolite cages. / Shailaja, J.; Ponchot, Keith J.; Ramamurthy, Vaidhyanathan.

In: Organic Letters, Vol. 2, No. 7, 06.04.2000, p. 937-940.

Research output: Contribution to journalArticle

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