Empirical assessment of the factorial structure of clinical symptoms in schizophrenia: Negative symptoms

Richard S.E. Keefe, Philip D. Harvey, Mark F. Lenzenweger, Michael Davidson, Seth H. Apter, James Schmeidler, Richard C. Mohs, Kenneth L. Davis

Research output: Contribution to journalArticle

82 Scopus citations

Abstract

The factor structure of the Scale for the Assessment of Negative Symptoms (SANS) was examined in a confirmatory factor analysis that used the LISREL procedure. Four models of negative symptom factors were tested in 130 hospitalized schizophrenic patients. A three-factor model of diminished expression, social dysfunction, and disorganization generated by the authors yielded a superior fit to the data relative to the two-factor model of Liddle (1987b) and a unifactorial severity model. A four-factor model based on the original subscale formulation of the SANS failed to fit the data.

Original languageEnglish (US)
Pages (from-to)153-165
Number of pages13
JournalPsychiatry Research
Volume44
Issue number2
DOIs
StatePublished - Nov 1992
Externally publishedYes

Keywords

  • Deficit syndrome
  • factor analysis
  • Scale for the Assessment of Negative Symptoms

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry
  • Psychology(all)

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    Keefe, R. S. E., Harvey, P. D., Lenzenweger, M. F., Davidson, M., Apter, S. H., Schmeidler, J., Mohs, R. C., & Davis, K. L. (1992). Empirical assessment of the factorial structure of clinical symptoms in schizophrenia: Negative symptoms. Psychiatry Research, 44(2), 153-165. https://doi.org/10.1016/0165-1781(92)90049-9