Abstract
Background Fetal echocardiography is the main modality of prenatal diagnosis of CHD. This study was done to describe the trends and benefits associated with prenatal diagnosis of complex CHD at a tertiary care centre.Methods Retrospective chart review of patients with complex CHD over an 18-year period was performed. Rates of prenatal detection along with early and late infant mortality outcomes were studied.Results Of 381 complex CHD patients born during the study period, 68.8% were diagnosed prenatally. Prenatal detection rate increased during the study period from low-50s in the first quarter to mid-80s in the last quarter (p=0.001). Rate of detection of conotruncal anomalies increased over the study period. No infant mortality benefit was noted with prenatal detection.Conclusions Improved obstetrical screening indications and techniques have contributed to higher proportions of prenatal diagnosis of complex CHD. However, prenatal diagnosis did not confer survival benefits in infancy in our study.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 270-276 |
| Number of pages | 7 |
| Journal | Cardiology in the Young |
| Volume | 29 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 1 2019 |
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Keywords
- complex CHD
- fetal echocardiography
- infant mortality
- Prenatal diagnosis
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Cardiology and Cardiovascular Medicine
Cite this
Emerging trends in the prenatal diagnosis of complex CHD and its influence on infant mortality in this cohort. / Gorla, Sudheer R.; Chakraborty, Abhishek; Garg, Ashish; Gugol, Rubee A.; Kardon, Richard; Swaminathan, Sethuraman.
In: Cardiology in the Young, Vol. 29, No. 3, 01.03.2019, p. 270-276.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Emerging trends in the prenatal diagnosis of complex CHD and its influence on infant mortality in this cohort
AU - Gorla, Sudheer R.
AU - Chakraborty, Abhishek
AU - Garg, Ashish
AU - Gugol, Rubee A.
AU - Kardon, Richard
AU - Swaminathan, Sethuraman
PY - 2019/3/1
Y1 - 2019/3/1
N2 - Background Fetal echocardiography is the main modality of prenatal diagnosis of CHD. This study was done to describe the trends and benefits associated with prenatal diagnosis of complex CHD at a tertiary care centre.Methods Retrospective chart review of patients with complex CHD over an 18-year period was performed. Rates of prenatal detection along with early and late infant mortality outcomes were studied.Results Of 381 complex CHD patients born during the study period, 68.8% were diagnosed prenatally. Prenatal detection rate increased during the study period from low-50s in the first quarter to mid-80s in the last quarter (p=0.001). Rate of detection of conotruncal anomalies increased over the study period. No infant mortality benefit was noted with prenatal detection.Conclusions Improved obstetrical screening indications and techniques have contributed to higher proportions of prenatal diagnosis of complex CHD. However, prenatal diagnosis did not confer survival benefits in infancy in our study.
AB - Background Fetal echocardiography is the main modality of prenatal diagnosis of CHD. This study was done to describe the trends and benefits associated with prenatal diagnosis of complex CHD at a tertiary care centre.Methods Retrospective chart review of patients with complex CHD over an 18-year period was performed. Rates of prenatal detection along with early and late infant mortality outcomes were studied.Results Of 381 complex CHD patients born during the study period, 68.8% were diagnosed prenatally. Prenatal detection rate increased during the study period from low-50s in the first quarter to mid-80s in the last quarter (p=0.001). Rate of detection of conotruncal anomalies increased over the study period. No infant mortality benefit was noted with prenatal detection.Conclusions Improved obstetrical screening indications and techniques have contributed to higher proportions of prenatal diagnosis of complex CHD. However, prenatal diagnosis did not confer survival benefits in infancy in our study.
KW - complex CHD
KW - fetal echocardiography
KW - infant mortality
KW - Prenatal diagnosis
UR - http://www.scopus.com/inward/record.url?scp=85063387703&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85063387703&partnerID=8YFLogxK
U2 - 10.1017/S1047951118002147
DO - 10.1017/S1047951118002147
M3 - Article
AN - SCOPUS:85063387703
VL - 29
SP - 270
EP - 276
JO - Cardiology in the Young
JF - Cardiology in the Young
SN - 1047-9511
IS - 3
ER -