Emerging treatments in alopecia

Leyre Falto-Aizpurua, Sonal Choudhary, Antonella Tosti

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Introduction: Alopecia is a common concern encountered in the medical practice. Treatment approach varies according to the type and severity of alopecia. However, available treatment options have limited efficacy and several adverse effects. Presently, there are different treatment options being studied to overcome these limitations. Additionally, cellular pathways involved in the pathophysiology of alopecia are further being clarified to potentially target pathogenic molecules.Areas covered: We searched the literature for recently published articles discussing new treatment options as well as mechanisms involved in alopecia. We discuss the use of stem cells, growth factors, cellular pathways and robotic hair transplant, among other emerging therapies used for alopecia.Expert opinion: Future looks very promising and new effective treatments such as janus kinase inhibitors could possibly be available for alopecia areata. The stem-cell technology is advancing and companies involved in hair follicle neogenesis are starting clinical trials on patients with androgenetic alopecia.

Original languageEnglish
Pages (from-to)545-556
Number of pages12
JournalExpert Opinion on Emerging Drugs
Volume19
Issue number4
DOIs
StatePublished - Jan 1 2014

Fingerprint

Alopecia
Therapeutics
Janus Kinases
Alopecia Areata
Stem Cell Factor
Hair Follicle
Expert Testimony
Robotics
Hair
Intercellular Signaling Peptides and Proteins
Stem Cells
Clinical Trials
Technology
Transplants

Keywords

  • Abatacept
  • Alopecia areata
  • Androgenetic alopecia
  • Bimatoprost
  • Chemotherapy-induced alopecia
  • Dutasteride
  • Excimer laser
  • Finasteride
  • Hair transplant
  • IL-2
  • Iron
  • Janus kinase inhibitors
  • Micropigmentation
  • Minoxidil
  • Pioglitazone
  • Platelet-rich plasma
  • Prostaglandin
  • Retinoids
  • Ruxolitinib
  • Scalp cooling
  • Scarring alopecia
  • Stem cells
  • Tofacitinib
  • Trichotillomania
  • Vitamin D
  • Wnt pathway

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

Cite this

Emerging treatments in alopecia. / Falto-Aizpurua, Leyre; Choudhary, Sonal; Tosti, Antonella.

In: Expert Opinion on Emerging Drugs, Vol. 19, No. 4, 01.01.2014, p. 545-556.

Research output: Contribution to journalArticle

Falto-Aizpurua, Leyre ; Choudhary, Sonal ; Tosti, Antonella. / Emerging treatments in alopecia. In: Expert Opinion on Emerging Drugs. 2014 ; Vol. 19, No. 4. pp. 545-556.
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