Emerging therapies to treat frailty syndrome in the elderly

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Frailty syndrome (FS) has become increasingly recognized as a major predictor of co-morbidities and mortality in older individuals. Interventions with the potential to benefit frail elders include nutritional supplementation (vitamins D, carotenoids, creatine, dehydroepiandrosterone (DHEA), and beta-hydroxy-beta-methylbutyrate) and exercise modalities (tai chi and cobblestone walking). While these have not been explicitly tested for their impact on FS, vitamin D supplementation appears to offer significant promise in enhancing long-term health of the elderly. Exercise modalities such as tai chi and cobblestone walking, because of probable low risk and ease of participation, may also confer benefit. Additional studies are needed to investigate interventions that directly prevent, delay, and/or ameliorate frailty. Successful therapies may well involve multi-component approaches utilizing a combination of medication, nutritional supplementation, and exercise.

Original languageEnglish
Pages (from-to)246-258
Number of pages13
JournalAlternative Medicine Review
Volume12
Issue number3
StatePublished - Sep 1 2007

Fingerprint

Tai Ji
Exercise
Vitamin D
Walking
Frail Elderly
Dehydroepiandrosterone
Creatine
Carotenoids
Therapeutics
Morbidity
Mortality
Health

ASJC Scopus subject areas

  • Medicine(all)
  • Complementary and alternative medicine

Cite this

Emerging therapies to treat frailty syndrome in the elderly. / Cherniack, Evan Paul; Florez, Hermes J; Troen, Bruce R.

In: Alternative Medicine Review, Vol. 12, No. 3, 01.09.2007, p. 246-258.

Research output: Contribution to journalArticle

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