Emerging ciprofloxacin-resistant Pseudomonas aeruginosa

Nauman A. Chaudhry; Harry W. Flynn; Timothy G. Murray; Homayoun Tabandeh; Mozart O. Mello; Darlene Miller

doi:10.1016/S0002-9394(99)00196-8

Emerging ciprofloxacin-resistant Pseudomonas aeruginosa

Nauman A. Chaudhry, Harry W. Flynn, Timothy G. Murray, Homayoun Tabandeh, Mozart O. Mello, Darlene Miller

Ophthalmology

Research output: Contribution to journal › Article

86 Scopus citations

Abstract

PURPOSE: To report a clinical series of ciprofloxacin-resistant ocular isolates of Pseudomonas aeruginosa from a tertiary care ophthalmic center.METHODS: Review of in vitro sensitivities of all ocular isolates of P. aeruginosa between July 1991 and September 1998. In vitro resistance was defined as a minimum inhibitory concentration of 4 or more μg per ml. RESULTS: Nine of 423 ocular isolates of P. aeruginosa showed in vitro resistance to ciprofloxacin. From 1991 to 1994, 0.44% (1/227) of ocular isolates were resistant to ciprofloxacin, whereas from 1995 to 1998, 4.1% (8/196) of ocular isolates showed in vitro resistance (P = .014).CONCLUSIONS: Ciprofloxacin-resistant P. aeruginosa has been identified in recent clinical ocular specimens. Ciprofloxacin resistance among ocular isolates of P. aeruginosa is a local and worldwide concern. Copyright (C) 1999 Elsevier Science Inc.

Original language	English (US)
Pages (from-to)	509-510
Number of pages	2
Journal	American journal of ophthalmology
Volume	128
Issue number	4
DOIs	https://doi.org/10.1016/S0002-9394(99)00196-8
State	Published - Oct 1999

ASJC Scopus subject areas

Ophthalmology

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Chaudhry, N. A., Flynn, H. W., Murray, T. G., Tabandeh, H., Mello, M. O., & Miller, D. (1999). Emerging ciprofloxacin-resistant Pseudomonas aeruginosa. American journal of ophthalmology, 128(4), 509-510. https://doi.org/10.1016/S0002-9394(99)00196-8

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title = "Emerging ciprofloxacin-resistant Pseudomonas aeruginosa",

abstract = "PURPOSE: To report a clinical series of ciprofloxacin-resistant ocular isolates of Pseudomonas aeruginosa from a tertiary care ophthalmic center.METHODS: Review of in vitro sensitivities of all ocular isolates of P. aeruginosa between July 1991 and September 1998. In vitro resistance was defined as a minimum inhibitory concentration of 4 or more μg per ml. RESULTS: Nine of 423 ocular isolates of P. aeruginosa showed in vitro resistance to ciprofloxacin. From 1991 to 1994, 0.44% (1/227) of ocular isolates were resistant to ciprofloxacin, whereas from 1995 to 1998, 4.1% (8/196) of ocular isolates showed in vitro resistance (P = .014).CONCLUSIONS: Ciprofloxacin-resistant P. aeruginosa has been identified in recent clinical ocular specimens. Ciprofloxacin resistance among ocular isolates of P. aeruginosa is a local and worldwide concern. Copyright (C) 1999 Elsevier Science Inc.",

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AU - Chaudhry, Nauman A.

AU - Flynn, Harry W.

AU - Murray, Timothy G.

AU - Tabandeh, Homayoun

AU - Mello, Mozart O.

AU - Miller, Darlene

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N2 - PURPOSE: To report a clinical series of ciprofloxacin-resistant ocular isolates of Pseudomonas aeruginosa from a tertiary care ophthalmic center.METHODS: Review of in vitro sensitivities of all ocular isolates of P. aeruginosa between July 1991 and September 1998. In vitro resistance was defined as a minimum inhibitory concentration of 4 or more μg per ml. RESULTS: Nine of 423 ocular isolates of P. aeruginosa showed in vitro resistance to ciprofloxacin. From 1991 to 1994, 0.44% (1/227) of ocular isolates were resistant to ciprofloxacin, whereas from 1995 to 1998, 4.1% (8/196) of ocular isolates showed in vitro resistance (P = .014).CONCLUSIONS: Ciprofloxacin-resistant P. aeruginosa has been identified in recent clinical ocular specimens. Ciprofloxacin resistance among ocular isolates of P. aeruginosa is a local and worldwide concern. Copyright (C) 1999 Elsevier Science Inc.

AB - PURPOSE: To report a clinical series of ciprofloxacin-resistant ocular isolates of Pseudomonas aeruginosa from a tertiary care ophthalmic center.METHODS: Review of in vitro sensitivities of all ocular isolates of P. aeruginosa between July 1991 and September 1998. In vitro resistance was defined as a minimum inhibitory concentration of 4 or more μg per ml. RESULTS: Nine of 423 ocular isolates of P. aeruginosa showed in vitro resistance to ciprofloxacin. From 1991 to 1994, 0.44% (1/227) of ocular isolates were resistant to ciprofloxacin, whereas from 1995 to 1998, 4.1% (8/196) of ocular isolates showed in vitro resistance (P = .014).CONCLUSIONS: Ciprofloxacin-resistant P. aeruginosa has been identified in recent clinical ocular specimens. Ciprofloxacin resistance among ocular isolates of P. aeruginosa is a local and worldwide concern. Copyright (C) 1999 Elsevier Science Inc.

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