Elevated aspartate aminotransferase-to-platelet ratio index in perinatally HIV-infected children in the United States

George K. Siberry, Kunjal Patel, Jorge A. Pinto, Ana Puga, Ayesha Mirza, Tracie L Miller, Russell B. Van Dyke

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Elevated aspartate aminotransferase-to-platelet ratio index may signal liver fibrosis. Among 397 US children with perinatal HIV infection, at baseline was >1.5 in 0.8% [95% confidence interval (CI), 0.2-2.2%) and >0.5 in 6.5% (95% CI, 4.3-9.4%); incidence on study was 0.5 (95% CI, 0.2-1.2) and 6.4 (95% CI, 4.8-8.3) per 100 person-years, respectively. Longterm liver outcomes after perinatal HIV infection warrant further study.

Original languageEnglish
Pages (from-to)855-857
Number of pages3
JournalPediatric Infectious Disease Journal
Volume33
Issue number8
DOIs
StatePublished - Jan 1 2014

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Aspartate Aminotransferases
Blood Platelets
HIV
Confidence Intervals
HIV Infections
Liver Cirrhosis
Cohort Studies
Liver

Keywords

  • APRI
  • HIV
  • Liver

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Infectious Diseases
  • Microbiology (medical)

Cite this

Elevated aspartate aminotransferase-to-platelet ratio index in perinatally HIV-infected children in the United States. / Siberry, George K.; Patel, Kunjal; Pinto, Jorge A.; Puga, Ana; Mirza, Ayesha; Miller, Tracie L; Van Dyke, Russell B.

In: Pediatric Infectious Disease Journal, Vol. 33, No. 8, 01.01.2014, p. 855-857.

Research output: Contribution to journalArticle

Siberry, George K. ; Patel, Kunjal ; Pinto, Jorge A. ; Puga, Ana ; Mirza, Ayesha ; Miller, Tracie L ; Van Dyke, Russell B. / Elevated aspartate aminotransferase-to-platelet ratio index in perinatally HIV-infected children in the United States. In: Pediatric Infectious Disease Journal. 2014 ; Vol. 33, No. 8. pp. 855-857.
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