Elevated aspartate aminotransferase-to-platelet ratio index in perinatally HIV-infected children in the United States

George K. Siberry; Kunjal Patel; Jorge A. Pinto; Ana Puga; Ayesha Mirza; Tracie L. Miller; Russell B. Van Dyke

doi:10.1097/INF.0000000000000348

Elevated aspartate aminotransferase-to-platelet ratio index in perinatally HIV-infected children in the United States

George K. Siberry, Kunjal Patel, Jorge A. Pinto, Ana Puga, Ayesha Mirza, Tracie L. Miller, Russell B. Van Dyke

Pediatrics

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Elevated aspartate aminotransferase-to-platelet ratio index may signal liver fibrosis. Among 397 US children with perinatal HIV infection, at baseline was >1.5 in 0.8% [95% confidence interval (CI), 0.2-2.2%) and >0.5 in 6.5% (95% CI, 4.3-9.4%); incidence on study was 0.5 (95% CI, 0.2-1.2) and 6.4 (95% CI, 4.8-8.3) per 100 person-years, respectively. Longterm liver outcomes after perinatal HIV infection warrant further study.

Original language	English (US)
Pages (from-to)	855-857
Number of pages	3
Journal	Pediatric Infectious Disease Journal
Volume	33
Issue number	8
DOIs	https://doi.org/10.1097/INF.0000000000000348
State	Published - Aug 2014

Keywords

APRI
HIV
Liver

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Infectious Diseases
Microbiology (medical)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/INF.0000000000000348

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Elevated aspartate aminotransferase-to-platelet ratio index in perinatally HIV-infected children in the United States. / Siberry, George K.; Patel, Kunjal; Pinto, Jorge A.; Puga, Ana; Mirza, Ayesha; Miller, Tracie L.; Van Dyke, Russell B.

In: Pediatric Infectious Disease Journal, Vol. 33, No. 8, 08.2014, p. 855-857.

Research output: Contribution to journal › Article › peer-review

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title = "Elevated aspartate aminotransferase-to-platelet ratio index in perinatally HIV-infected children in the United States",

abstract = "Elevated aspartate aminotransferase-to-platelet ratio index may signal liver fibrosis. Among 397 US children with perinatal HIV infection, at baseline was >1.5 in 0.8% [95% confidence interval (CI), 0.2-2.2%) and >0.5 in 6.5% (95% CI, 4.3-9.4%); incidence on study was 0.5 (95% CI, 0.2-1.2) and 6.4 (95% CI, 4.8-8.3) per 100 person-years, respectively. Longterm liver outcomes after perinatal HIV infection warrant further study.",

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AU - Puga, Ana

AU - Mirza, Ayesha

AU - Miller, Tracie L.

AU - Van Dyke, Russell B.

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Elevated aspartate aminotransferase-to-platelet ratio index in perinatally HIV-infected children in the United States

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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