Elevated aspartate aminotransferase-to-platelet ratio index in perinatally HIV-infected children in the United States

George K. Siberry; Kunjal Patel; Jorge A. Pinto; Ana Puga; Ayesha Mirza; Tracie L. Miller; Russell B. Van Dyke

doi:10.1097/INF.0000000000000348

Elevated aspartate aminotransferase-to-platelet ratio index in perinatally HIV-infected children in the United States

George K. Siberry, Kunjal Patel, Jorge A. Pinto, Ana Puga, Ayesha Mirza, Tracie L. Miller, Russell B. Van Dyke

Pediatrics

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Elevated aspartate aminotransferase-to-platelet ratio index may signal liver fibrosis. Among 397 US children with perinatal HIV infection, at baseline was >1.5 in 0.8% [95% confidence interval (CI), 0.2-2.2%) and >0.5 in 6.5% (95% CI, 4.3-9.4%); incidence on study was 0.5 (95% CI, 0.2-1.2) and 6.4 (95% CI, 4.8-8.3) per 100 person-years, respectively. Longterm liver outcomes after perinatal HIV infection warrant further study.

Original language	English (US)
Pages (from-to)	855-857
Number of pages	3
Journal	Pediatric Infectious Disease Journal
Volume	33
Issue number	8
DOIs	https://doi.org/10.1097/INF.0000000000000348
State	Published - Aug 2014

Keywords

APRI
HIV
Liver

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Infectious Diseases
Microbiology (medical)

UN SDGs

This output contributes to the following Sustainable Development Goal(s)

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10.1097/INF.0000000000000348

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Elevated aspartate aminotransferase-to-platelet ratio index in perinatally HIV-infected children in the United States. / Siberry, George K.; Patel, Kunjal; Pinto, Jorge A.; Puga, Ana; Mirza, Ayesha; Miller, Tracie L.; Van Dyke, Russell B.

In: Pediatric Infectious Disease Journal, Vol. 33, No. 8, 08.2014, p. 855-857.

Research output: Contribution to journal › Article › peer-review

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abstract = "Elevated aspartate aminotransferase-to-platelet ratio index may signal liver fibrosis. Among 397 US children with perinatal HIV infection, at baseline was >1.5 in 0.8% [95% confidence interval (CI), 0.2-2.2%) and >0.5 in 6.5% (95% CI, 4.3-9.4%); incidence on study was 0.5 (95% CI, 0.2-1.2) and 6.4 (95% CI, 4.8-8.3) per 100 person-years, respectively. Longterm liver outcomes after perinatal HIV infection warrant further study.",

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AU - Puga, Ana

AU - Mirza, Ayesha

AU - Miller, Tracie L.

AU - Van Dyke, Russell B.

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Elevated aspartate aminotransferase-to-platelet ratio index in perinatally HIV-infected children in the United States

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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