Electrolytes of the gastric juice in health and gastroduodenal diseases

Jose Carlos Meeroff, Jorge Alberto Rofrano, Marcos Meeroff

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13 Scopus citations


The results of using a new procedure for performing gastric analysis, called "gastroionogram," are described. The procedure provides measurements of hydrogen, sodium, potassium, and chloride in the gastric content. The results are expressed as concentrations and outputs of these ions. A total of 2327 studies were carried out between 1965 and 1971, using different stimulants to obtain gastric juice, and analysis of the results allows the following conclusions: a) secretory response is similar with any potent stimulus; b) collection between 15 and 75 minutes after stimulation is a reliable and valid "1-hour" stimulated period; and c) the outputs of ions, perhaps those of hydrogen and sodium, are potentially useful for the diagnosis of several pathologic groups-active duodenal ulcer, Zollinger-Ellison syndrome, peptic gastric ulcer, trophic gastric ulcer, and chronic gastritis. Except for the last two, the groups also show differences among themselves.

Original languageEnglish (US)
Pages (from-to)865-872
Number of pages8
JournalThe American Journal of Digestive Diseases
Issue number10
StatePublished - Oct 1 1973

ASJC Scopus subject areas

  • Gastroenterology


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