Electrodiffusion model simulation of ionic channels: 1D simulations

Carl L. Gardner, Wolfgang Nonner, Robert S. Eisenberg

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

The drift-diffusion (Poisson-Nernst-Planck) model is applied to ionic channels in biological membranes plus surrounding solution baths. Simulations of the K channel in KCl solutions using the TRBDF2 method are presented which show significant boundary layers at the ends of the channel. The computed current-voltage curve for the K channel shows excellent agreement with experimental measurements.

Original languageEnglish (US)
Pages (from-to)25-31
Number of pages7
JournalJournal of Computational Electronics
Volume3
Issue number1
DOIs
StatePublished - Dec 1 2004

Keywords

  • Biological channels
  • Diffusion models
  • Ion transport

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Modeling and Simulation

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