Electrodiffusion model simulation of ionic channels: 1D simulations

Carl L. Gardner, Wolfgang Nonner, Robert S. Eisenberg

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

The drift-diffusion (Poisson-Nernst-Planck) model is applied to ionic channels in biological membranes plus surrounding solution baths. Simulations of the K channel in KCl solutions using the TRBDF2 method are presented which show significant boundary layers at the ends of the channel. The computed current-voltage curve for the K channel shows excellent agreement with experimental measurements.

Original languageEnglish
Pages (from-to)25-31
Number of pages7
JournalJournal of Computational Electronics
Volume3
Issue number1
DOIs
StatePublished - Dec 1 2004
Externally publishedYes

Fingerprint

K+ Channel
Ion Channels
Simulation Model
Biological membranes
Drift-diffusion
Boundary Layer
Siméon Denis Poisson
Boundary layers
Simulation
Membrane
simulation
Voltage
Curve
Electric potential
baths
boundary layers
membranes
electric potential
curves
Model

Keywords

  • Biological channels
  • Diffusion models
  • Ion transport

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Modeling and Simulation

Cite this

Electrodiffusion model simulation of ionic channels : 1D simulations. / Gardner, Carl L.; Nonner, Wolfgang; Eisenberg, Robert S.

In: Journal of Computational Electronics, Vol. 3, No. 1, 01.12.2004, p. 25-31.

Research output: Contribution to journalArticle

Gardner, Carl L. ; Nonner, Wolfgang ; Eisenberg, Robert S. / Electrodiffusion model simulation of ionic channels : 1D simulations. In: Journal of Computational Electronics. 2004 ; Vol. 3, No. 1. pp. 25-31.
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