Electrocardiographic comparison of myocardial salvage with primary revascularization versus thrombolysis in inferior myocardial infarction

Michael P. Hudson, Mauricio G. Cohen, Charles Maynard, Janet Patterson, Paul T. Campbell, Kevin Kruse, Galen S. Wagner

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Primary revascularization (PR) and thrombolytic therapy (TT) reduce infarct size and mortality in patients with ST-segment elevation acute myocardial infarction (AMI). Electrocardiogram methods can determine the extent of myocardial salvage with different AMI therapies by comparing infarct size predicted by initial ST-segment changes and infarct size estimated by later quantitative QRS scores. In a community hospital setting, we used quantitative electrocardiogram methods to estimate infarct size and myocardial salvage associated with TT and PR amongst 50 patients presenting with inferior ST-segment elevation AMI. Baseline and electrocardiogram characteristics did not differ between TT (n = 29) and PR (n = 21) patients. There was no difference in median myocardial salvage (%) between TT vs. PR groups, (38.3% vs. 44.9% respectively, P = .66). Among patients with inferior AMI, myocardial salvage was achieved with both TT and PR therapy and did not differ significantly between reperfusion strategies.

Original languageEnglish (US)
Pages (from-to)11-18
Number of pages8
JournalJournal of Electrocardiology
Volume35
Issue number1
DOIs
StatePublished - Jan 1 2002

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Keywords

  • Electrocardiogram
  • Myocardial infarction
  • Myocardial salvage
  • Reperfusion therapy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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