Abstract
The osmorespiratory compromise, the trade-off between the requirements for respiratory and ionoregulatory homeostasis at the gills, becomes more intense during environmental hypoxia. One aspect that has been previously overlooked is possible change in transepithelial potential (TEP) caused by hypoxia, which will influence branchial ionic fluxes. Using the euryhaline killifish, we show that acute hypoxia reduces the TEP across the gills by approximately 10 mV in animals acclimated to both freshwater (FW) and seawater (SW), with a higher PO2 threshold in the former. TEP becomes negative in FW, and less positive in SW. The effects are immediate, stable for at least 3 h, and reverse immediately upon return to normoxia. Hypoxia also blocks the normal increase in TEP that occurs upon transfer from FW to SW, but does not reduce the fall in TEP that occurs with transfer in the opposite direction. These effects may be beneficial in FW but not in SW.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2152-2155 |
| Number of pages | 4 |
| Journal | Journal of Experimental Biology |
| Volume | 218 |
| Issue number | 14 |
| DOIs | |
| State | Published - Jul 1 2015 |
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Keywords
- Diffusion potential
- Electrogenic potential
- Gill permeability
- P/P ratio
- Transepithelial potential
ASJC Scopus subject areas
- Animal Science and Zoology
- Ecology, Evolution, Behavior and Systematics
- Molecular Biology
- Physiology
- Insect Science
- Aquatic Science
Cite this
Electrical aspects of the osmorespiratory compromise : TEP responses to hypoxia in the euryhaline killifish (Fundulus heteroclitus) in freshwater and seawater. / Wood, Chris M.; Grosell, Martin.
In: Journal of Experimental Biology, Vol. 218, No. 14, 01.07.2015, p. 2152-2155.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Electrical aspects of the osmorespiratory compromise
T2 - TEP responses to hypoxia in the euryhaline killifish (Fundulus heteroclitus) in freshwater and seawater
AU - Wood, Chris M.
AU - Grosell, Martin
PY - 2015/7/1
Y1 - 2015/7/1
N2 - The osmorespiratory compromise, the trade-off between the requirements for respiratory and ionoregulatory homeostasis at the gills, becomes more intense during environmental hypoxia. One aspect that has been previously overlooked is possible change in transepithelial potential (TEP) caused by hypoxia, which will influence branchial ionic fluxes. Using the euryhaline killifish, we show that acute hypoxia reduces the TEP across the gills by approximately 10 mV in animals acclimated to both freshwater (FW) and seawater (SW), with a higher PO2 threshold in the former. TEP becomes negative in FW, and less positive in SW. The effects are immediate, stable for at least 3 h, and reverse immediately upon return to normoxia. Hypoxia also blocks the normal increase in TEP that occurs upon transfer from FW to SW, but does not reduce the fall in TEP that occurs with transfer in the opposite direction. These effects may be beneficial in FW but not in SW.
AB - The osmorespiratory compromise, the trade-off between the requirements for respiratory and ionoregulatory homeostasis at the gills, becomes more intense during environmental hypoxia. One aspect that has been previously overlooked is possible change in transepithelial potential (TEP) caused by hypoxia, which will influence branchial ionic fluxes. Using the euryhaline killifish, we show that acute hypoxia reduces the TEP across the gills by approximately 10 mV in animals acclimated to both freshwater (FW) and seawater (SW), with a higher PO2 threshold in the former. TEP becomes negative in FW, and less positive in SW. The effects are immediate, stable for at least 3 h, and reverse immediately upon return to normoxia. Hypoxia also blocks the normal increase in TEP that occurs upon transfer from FW to SW, but does not reduce the fall in TEP that occurs with transfer in the opposite direction. These effects may be beneficial in FW but not in SW.
KW - Diffusion potential
KW - Electrogenic potential
KW - Gill permeability
KW - P/P ratio
KW - Transepithelial potential
UR - http://www.scopus.com/inward/record.url?scp=84955510041&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84955510041&partnerID=8YFLogxK
U2 - 10.1242/jeb.122176
DO - 10.1242/jeb.122176
M3 - Article
C2 - 26026034
AN - SCOPUS:84955510041
VL - 218
SP - 2152
EP - 2155
JO - Journal of Experimental Biology
JF - Journal of Experimental Biology
SN - 0022-0949
IS - 14
ER -