Efficient quenching of oligomeric fluorophores on a DNA backbone

James N Wilson, Nah Teo Yin, Eric T. Kool

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

The quenching properties of a series of oligodeoxyribosides bearing fluorophore "bases" are described. Sequences of adjacent, π-stacked pyrenes exhibit stronger electronic interactions visible in both absorbance and emission spectra than pyrenes that are insulated by intervening adenines. Quenching by N,N-dimethyl-4,4′-bipyridinium dichloride is efficient for excimer- and exciplex-forming oligomers, with Stern-Volmer constants comparable to conjugated polymer "superquenching" schemes.

Original languageEnglish
Pages (from-to)15426-15427
Number of pages2
JournalJournal of the American Chemical Society
Volume129
Issue number50
DOIs
StatePublished - Dec 19 2007
Externally publishedYes

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Pyrenes
Fluorophores
Pyrene
Quenching
DNA
Bearings (structural)
Conjugated polymers
Adenine
Oligomers
Polymers

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Efficient quenching of oligomeric fluorophores on a DNA backbone. / Wilson, James N; Yin, Nah Teo; Kool, Eric T.

In: Journal of the American Chemical Society, Vol. 129, No. 50, 19.12.2007, p. 15426-15427.

Research output: Contribution to journalArticle

Wilson, James N ; Yin, Nah Teo ; Kool, Eric T. / Efficient quenching of oligomeric fluorophores on a DNA backbone. In: Journal of the American Chemical Society. 2007 ; Vol. 129, No. 50. pp. 15426-15427.
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