Abstract
We assessed the in vitro antimicrobial activity and the in vivo efficacy of dipping ventricular assist devices in a combination of N-acetylcysteine, gentamicin, and amphotericin B (NAC/G/A). Ventricular assist devices dipped in NAC/G/A exhibited broad-spectrum antimicrobial activity in vitro and were less likely than undipped devices to become colonized with Staphylococcus aureus in a rabbit model.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 190-192 |
| Number of pages | 3 |
| Journal | Infection control and hospital epidemiology |
| Volume | 30 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 1 2009 |
ASJC Scopus subject areas
- Epidemiology
- Microbiology (medical)
- Infectious Diseases
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Hernandez, M. D., Mansouri, M. D., Aslam, S., Zeluff, B., & Darouiche, R. O. (2009). Efficacy of combination of N-acetylcysteine, gentamicin, and amphotericin B for prevention of microbial colonization of ventricular assist devices. Infection control and hospital epidemiology, 30(2), 190-192. https://doi.org/10.1086/593205