TY - JOUR
T1 - Effects of weight loss after gastric bypass on right and left ventricular function assessed by tissue doppler imaging
AU - Willens, Howard J
AU - Chakko, Simon C
AU - Byers, Patricia
AU - Chirinos, Julio A.
AU - Labrador, Eugenio
AU - Castrillon, Juan C.
AU - Lowery, Maureen H.
PY - 2005/6/15
Y1 - 2005/6/15
N2 - To evaluate the effects of substantial weight loss on tissue Doppler imaging parameters of right ventricular (RV) and left ventricular (LV) systolic and diastolic function, we performed standard echocardiography and tissue Doppler imaging in 17 patients with severe obesity before and after gastric bypass. Patients lost 39 ± 10 kg over 7.6 ± 3.6 months. Adjusted LV mass decreased (134 ± 41 to 119 ± 31 kg/m, p = 0.031). After weight loss, the ratios of early-to-late diastolic mitral and tricuspid inflow velocities increased (1.3 ± 0.2 to 1.6 ± 0.5, p = 0.02; 1.0 ± 0.1 to 1.6 ± 0.3, p = 0.003). Early diastolic tissue Doppler velocities increased at both the lateral and septal mitral annulus (7.6 ± 1.5 to 9.3 ± 2.5 cm/s, p = 0.009; and 6.6 ± 1.4 to 7.7 ± 1.7 cm/s; p = 0.028, respectively) and for their 2-site average (7.2 ± 1.0 to 8.5 ± 1.7 cm/s, p = 0.007). Early diastolic tricuspid annular velocity increased (7.2 ± 2.8 to 10.6 ± 2.3 cm/s, p <0.001) as did the ratio of early-to-late tricuspid annular diastolic velocity (0.9 ± 0.4 to 1.1 ± 0.2, p = 0.038). Tricuspid annular systolic velocity increased (8.6 ± 2.5 to 10.3 ± 2.7 cm/s, p = 0.037). In patients with severe obesity, significant weight loss results in an increase in tricuspid annular systolic and early diastolic velocities and mitral annular early diastolic velocities.
AB - To evaluate the effects of substantial weight loss on tissue Doppler imaging parameters of right ventricular (RV) and left ventricular (LV) systolic and diastolic function, we performed standard echocardiography and tissue Doppler imaging in 17 patients with severe obesity before and after gastric bypass. Patients lost 39 ± 10 kg over 7.6 ± 3.6 months. Adjusted LV mass decreased (134 ± 41 to 119 ± 31 kg/m, p = 0.031). After weight loss, the ratios of early-to-late diastolic mitral and tricuspid inflow velocities increased (1.3 ± 0.2 to 1.6 ± 0.5, p = 0.02; 1.0 ± 0.1 to 1.6 ± 0.3, p = 0.003). Early diastolic tissue Doppler velocities increased at both the lateral and septal mitral annulus (7.6 ± 1.5 to 9.3 ± 2.5 cm/s, p = 0.009; and 6.6 ± 1.4 to 7.7 ± 1.7 cm/s; p = 0.028, respectively) and for their 2-site average (7.2 ± 1.0 to 8.5 ± 1.7 cm/s, p = 0.007). Early diastolic tricuspid annular velocity increased (7.2 ± 2.8 to 10.6 ± 2.3 cm/s, p <0.001) as did the ratio of early-to-late tricuspid annular diastolic velocity (0.9 ± 0.4 to 1.1 ± 0.2, p = 0.038). Tricuspid annular systolic velocity increased (8.6 ± 2.5 to 10.3 ± 2.7 cm/s, p = 0.037). In patients with severe obesity, significant weight loss results in an increase in tricuspid annular systolic and early diastolic velocities and mitral annular early diastolic velocities.
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U2 - 10.1016/j.amjcard.2005.02.029
DO - 10.1016/j.amjcard.2005.02.029
M3 - Article
C2 - 15950589
AN - SCOPUS:20444504384
VL - 95
SP - 1521
EP - 1524
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 12
ER -