Effects of waterborne silver in a marine teleost, the gulf toadfish (Opsanus beta): Effects of feeding and chronic exposure on bioaccumulation and physiological responses

Chris M. Wood, Martin Grosell, Danielle M Mcdonald, Richard C. Playle, Patrick J. Walsh

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Marine teleosts drink seawater, and the digestive tract is a key organ of osmoregulation. The gastro-intestinal tract therefore offers a second site for the potential uptake and toxicity of waterborne metals, but how these processes might interact with the digestive functions of the tract has not been investigated previously. We therefore compared the responses of adult gulf toadfish (Opsanus beta, collected from the wild) to a chronic 22d exposure to waterborne Ag (nominally 200μgL-1=1.85μmolL-1), in the presence or absence of daily satiation feeding (shrimp). Ag exposure did not affect voluntary feeding rate. Feeding reduced the net whole body accumulation of Ag by >50%, with reductions in liver concentrations (high) and white muscle concentrations (relatively low) playing the largest quantitative roles. Feeding also protected against Ag buildup in the esophagus-stomach and kidney, and increased biliary and urinary Ag concentrations. The gill was the only tissue to show the opposite response. Although terminal plasma Na+, Cl-, and Mg2+ concentrations were unaffected, there were complex interactive effects on osmoregulatory functions of the gastro-intestinal tract, including drinking rate, gut fluid volumes, and intestinal base secretion rates. At the end of the exposure, the plasma clearance kinetics of an arterially injected tracer dose of 110mAg were faster in toadfish that had been chronically exposed to waterborne Ag, and 110mAg accumulation in their red blood cells was reduced. After 32h, higher amounts of 110mAg were found in bile and urine, but lower amounts in the intestine of the Ag-exposed toadfish; there were no other differences in tissue-specific distribution. The results suggest that feeding reduces waterborne Ag uptake through the digestive tract and alters physiological responses, while chronic exposure enhances regulatory functions. The time-dependent actions of the liver in Ag scavenging and detoxification are highlighted.

Original languageEnglish
Pages (from-to)138-148
Number of pages11
JournalAquatic Toxicology
Volume99
Issue number2
DOIs
StatePublished - Aug 1 2010

Fingerprint

Batrachoidiformes
Batrachoididae
bioaccumulation
chronic exposure
physiological response
teleost
Silver
digestive tract
silver
gastrointestinal system
uptake mechanisms
Gastrointestinal Tract
liver
osmoregulation
esophagus
bile
satiety
drinking
tracer techniques
gills

Keywords

  • Ag
  • Bile
  • Clearance kinetics
  • Drinking
  • Gastrointestinal tract
  • Kidney
  • Red blood cells

ASJC Scopus subject areas

  • Aquatic Science
  • Health, Toxicology and Mutagenesis

Cite this

Effects of waterborne silver in a marine teleost, the gulf toadfish (Opsanus beta) : Effects of feeding and chronic exposure on bioaccumulation and physiological responses. / Wood, Chris M.; Grosell, Martin; Mcdonald, Danielle M; Playle, Richard C.; Walsh, Patrick J.

In: Aquatic Toxicology, Vol. 99, No. 2, 01.08.2010, p. 138-148.

Research output: Contribution to journalArticle

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abstract = "Marine teleosts drink seawater, and the digestive tract is a key organ of osmoregulation. The gastro-intestinal tract therefore offers a second site for the potential uptake and toxicity of waterborne metals, but how these processes might interact with the digestive functions of the tract has not been investigated previously. We therefore compared the responses of adult gulf toadfish (Opsanus beta, collected from the wild) to a chronic 22d exposure to waterborne Ag (nominally 200μgL-1=1.85μmolL-1), in the presence or absence of daily satiation feeding (shrimp). Ag exposure did not affect voluntary feeding rate. Feeding reduced the net whole body accumulation of Ag by >50{\%}, with reductions in liver concentrations (high) and white muscle concentrations (relatively low) playing the largest quantitative roles. Feeding also protected against Ag buildup in the esophagus-stomach and kidney, and increased biliary and urinary Ag concentrations. The gill was the only tissue to show the opposite response. Although terminal plasma Na+, Cl-, and Mg2+ concentrations were unaffected, there were complex interactive effects on osmoregulatory functions of the gastro-intestinal tract, including drinking rate, gut fluid volumes, and intestinal base secretion rates. At the end of the exposure, the plasma clearance kinetics of an arterially injected tracer dose of 110mAg were faster in toadfish that had been chronically exposed to waterborne Ag, and 110mAg accumulation in their red blood cells was reduced. After 32h, higher amounts of 110mAg were found in bile and urine, but lower amounts in the intestine of the Ag-exposed toadfish; there were no other differences in tissue-specific distribution. The results suggest that feeding reduces waterborne Ag uptake through the digestive tract and alters physiological responses, while chronic exposure enhances regulatory functions. The time-dependent actions of the liver in Ag scavenging and detoxification are highlighted.",
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