Effects of vaginal intercourse with and without a condom on vaginal flora and vaginal epithelium

David A. Eschenbach, Dorothy L. Patton, Thomas M. Hooton, Amalia S. Meier, Ann Stapleton, Jan Aura, Kathy Agnew

Research output: Contribution to journalArticle

44 Scopus citations

Abstract

Effects of a single episode of intercourse on vaginal flora and epithelium were examined in subjects randomly assigned to groups that used no condom or lubricated nonspermicide condoms. Subjects were evaluated at visits before (1 month and 1-2 days) and after (8-12 h, 2-3 days, and 6-8 days) an index episode of sexual intercourse. The 22 subjects who used no condoms had significantly more Escherichia coli and a high concentration (≥105 cfu/mL) of E. coli in the vagina (both, P < .001) and urine (all <105 cfu/mL; P = .004) at visit 3 than at visits 1 and 2. The 20 subjects who used condoms had a trend toward more vaginal E, coli (P = .06) and a significant increase in other enteric gram-negative rods (P = .001) after intercourse. Intercourse was not associated with gross, colposcopic, or histologic vaginal epithelial abnormalities.

Original languageEnglish (US)
Pages (from-to)913-918
Number of pages6
JournalJournal of Infectious Diseases
Volume183
Issue number6
DOIs
StatePublished - Mar 15 2001
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

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    Eschenbach, D. A., Patton, D. L., Hooton, T. M., Meier, A. S., Stapleton, A., Aura, J., & Agnew, K. (2001). Effects of vaginal intercourse with and without a condom on vaginal flora and vaginal epithelium. Journal of Infectious Diseases, 183(6), 913-918. https://doi.org/10.1086/319251