Effects of stress management on PNI-based outcomes in persons with HIV disease

Nancy L. McCain, Barbara A. Munjas, Cindy L. Munro, R. K. Elswick, Jo L. Wheeler Robins, Andrea Ferreira-Gonzalez, Beverly Baliko, Lisa G. Kaplowitz, Evelyn J. Fisher, Carleton T. Garrett, Kevin E. Brigle, Linda C. Kendall, Valentina Lucas, Katherine L. Cochran

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27 Scopus citations


A pretest-posttest, repeated-measures design was used to evaluate the effects of two stress management interventions on a battery of outcomes derived from a psychoneuroimmunological (PNI) framework. The effects of cognitive-behavioral relaxation training groups (CBSM) and social support groups (SSG) were compared with a WAIT-listed control group on the outcomes of psychosocial functioning, quality of life, neuroendocrine mediation, and somatic health. Participants were 148 individuals (119 men, 29 women), diagnosed with HIV disease; 112 (76%) completing the study groups. Using analysis of covariance, the CBSM group was found to have significantly higher postintervention emotional well-being and total quality-of-life scores than did either the SSG or WAIT groups. SSG participants had significantly lower social/family well-being scores immediately postintervention and lower social support scores after 6 months. The findings point to a pressing need for further, well-controlled research with these common intervention modalities.

Original languageEnglish (US)
Pages (from-to)102-117
Number of pages16
JournalResearch in Nursing and Health
Issue number2
StatePublished - Apr 2003


  • Nursing interventions
  • Psychoneuroimmunology
  • Stress management

ASJC Scopus subject areas

  • Nursing(all)

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    McCain, N. L., Munjas, B. A., Munro, C. L., Elswick, R. K., Wheeler Robins, J. L., Ferreira-Gonzalez, A., Baliko, B., Kaplowitz, L. G., Fisher, E. J., Garrett, C. T., Brigle, K. E., Kendall, L. C., Lucas, V., & Cochran, K. L. (2003). Effects of stress management on PNI-based outcomes in persons with HIV disease. Research in Nursing and Health, 26(2), 102-117. https://doi.org/10.1002/nur.10074