Effects of lipids and antioxidants on PCB-mediated dysfunction of vascular endothelial cells (EC)

B. Hennig, R. Slim, M. Toborek, A. Malecki, L. W. Robertson

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Our findings suggest that exposure to specific environmental contaminants can trigger diseases of the vasculature, e.g., cardiovascular disease. In addition, high-fat diets may potentiate and diets high in antioxidant nutrients may protect against PCB-mediated endothelial cell dysfunction. Our data give an insight into the potential use of vitamin E and related antioxidants to limit PCB-mediated cell injury. These studies are significant for providing new insights into potential nutrition interventions in diseases that can be induced by the toxicity of PCBs and other halogenated compounds.

Original languageEnglish (US)
Pages (from-to)18-19
Number of pages2
JournalCentral European Journal of Public Health
Volume8
Issue numberSUPPL.
StatePublished - Jul 2000
Externally publishedYes

Keywords

  • Atherosclerosis
  • Endothelial cells
  • Fatty acids
  • PCB
  • Vitamin E

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

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