Effects of H-Phe-Ile-Tyr-His-Ser-Tyr-Lys-OH on different behavioral tests of rats

L. Vécsei, I. Bollók, G. Telegdy, Andrew V Schally

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

H-Phe-Ile-Tyr-His-Ser-Tyr-Lys-OH inhibited the extinction of active avoidance behavior 3 h and 6 h after administration and facilitated the learning of a T-discrimination task. The peptide antagonized ECS-induced amnesia, if the treatment was performed 1h before the test session. These results suggest that H-Phe-Ile-Tyr-His-Ser-Tyr-Lys-OH can facilitate learning and memory processes.

Original languageEnglish
Pages (from-to)625-627
Number of pages3
JournalExperimental Brain Research
Volume57
Issue number3
DOIs
StatePublished - Feb 1 1985
Externally publishedYes

Fingerprint

Learning
Avoidance Learning
Amnesia
Peptides
Behavior Rating Scale
H-phenylalanyl-isoleucyl-tyrosyl-histidyl-seryl-tyrosyl-lysine
Discrimination (Psychology)
Psychological Extinction

Keywords

  • Active avoidance behavior
  • Discrimination learning
  • Hypothalamic peptide
  • Retrograde amnesia

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Effects of H-Phe-Ile-Tyr-His-Ser-Tyr-Lys-OH on different behavioral tests of rats. / Vécsei, L.; Bollók, I.; Telegdy, G.; Schally, Andrew V.

In: Experimental Brain Research, Vol. 57, No. 3, 01.02.1985, p. 625-627.

Research output: Contribution to journalArticle

Vécsei, L. ; Bollók, I. ; Telegdy, G. ; Schally, Andrew V. / Effects of H-Phe-Ile-Tyr-His-Ser-Tyr-Lys-OH on different behavioral tests of rats. In: Experimental Brain Research. 1985 ; Vol. 57, No. 3. pp. 625-627.
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