Effects of H-Phe-Ile-Tyr-His-Ser-Tyr-Lys-OH on different behavioral tests of rats

L. Vécsei, I. Bollók, G. Telegdy, A. V. Schally

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

H-Phe-Ile-Tyr-His-Ser-Tyr-Lys-OH inhibited the extinction of active avoidance behavior 3 h and 6 h after administration and facilitated the learning of a T-discrimination task. The peptide antagonized ECS-induced amnesia, if the treatment was performed 1h before the test session. These results suggest that H-Phe-Ile-Tyr-His-Ser-Tyr-Lys-OH can facilitate learning and memory processes.

Original languageEnglish (US)
Pages (from-to)625-627
Number of pages3
JournalExperimental Brain Research
Volume57
Issue number3
DOIs
StatePublished - Feb 1 1985
Externally publishedYes

Keywords

  • Active avoidance behavior
  • Discrimination learning
  • Hypothalamic peptide
  • Retrograde amnesia

ASJC Scopus subject areas

  • Neuroscience(all)

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