Abstract
H-Phe-Ile-Tyr-His-Ser-Tyr-Lys-OH inhibited the extinction of active avoidance behavior 3 h and 6 h after administration and facilitated the learning of a T-discrimination task. The peptide antagonized ECS-induced amnesia, if the treatment was performed 1h before the test session. These results suggest that H-Phe-Ile-Tyr-His-Ser-Tyr-Lys-OH can facilitate learning and memory processes.
| Original language | English |
|---|---|
| Pages (from-to) | 625-627 |
| Number of pages | 3 |
| Journal | Experimental Brain Research |
| Volume | 57 |
| Issue number | 3 |
| DOIs | |
| State | Published - Feb 1 1985 |
| Externally published | Yes |
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Keywords
- Active avoidance behavior
- Discrimination learning
- Hypothalamic peptide
- Retrograde amnesia
ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Effects of H-Phe-Ile-Tyr-His-Ser-Tyr-Lys-OH on different behavioral tests of rats. / Vécsei, L.; Bollók, I.; Telegdy, G.; Schally, Andrew V.
In: Experimental Brain Research, Vol. 57, No. 3, 01.02.1985, p. 625-627.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effects of H-Phe-Ile-Tyr-His-Ser-Tyr-Lys-OH on different behavioral tests of rats
AU - Vécsei, L.
AU - Bollók, I.
AU - Telegdy, G.
AU - Schally, Andrew V
PY - 1985/2/1
Y1 - 1985/2/1
N2 - H-Phe-Ile-Tyr-His-Ser-Tyr-Lys-OH inhibited the extinction of active avoidance behavior 3 h and 6 h after administration and facilitated the learning of a T-discrimination task. The peptide antagonized ECS-induced amnesia, if the treatment was performed 1h before the test session. These results suggest that H-Phe-Ile-Tyr-His-Ser-Tyr-Lys-OH can facilitate learning and memory processes.
AB - H-Phe-Ile-Tyr-His-Ser-Tyr-Lys-OH inhibited the extinction of active avoidance behavior 3 h and 6 h after administration and facilitated the learning of a T-discrimination task. The peptide antagonized ECS-induced amnesia, if the treatment was performed 1h before the test session. These results suggest that H-Phe-Ile-Tyr-His-Ser-Tyr-Lys-OH can facilitate learning and memory processes.
KW - Active avoidance behavior
KW - Discrimination learning
KW - Hypothalamic peptide
KW - Retrograde amnesia
UR - http://www.scopus.com/inward/record.url?scp=0021927770&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021927770&partnerID=8YFLogxK
U2 - 10.1007/BF00237850
DO - 10.1007/BF00237850
M3 - Article
VL - 57
SP - 625
EP - 627
JO - Experimental Brain Research
JF - Experimental Brain Research
SN - 0014-4819
IS - 3
ER -