Effects of erythropoietin on strength and functional status of patients on hemodialysis

M. Guthrie, D. Gardenas, J. W. Eschbach, N. R. Haley, H. T. Robertson, R. W. Evans

Research output: Contribution to journalArticle

42 Scopus citations

Abstract

The strength, endurance, and functional status of 15 anemic (HCT 21.2 ± 4.6) hemodialysis patients was quantified prior to the administration of erythropoietin (epoetin) and after the anemia was partially corrected (HCT 35.4 ± 2.3). Subjects showed significant increases in strength, measured isometrically (p < .01) and isokinetically (p < .01 at four of five speeds). They also demonstrated improved endurance and rated their functional ability higher. Anemia contributes to significant debilitation in hemodialysis patients and, when reversed with epoetin therapy, results in significantly improved muscle function and endurance.

Original languageEnglish (US)
Pages (from-to)97-102
Number of pages6
JournalClinical Nephrology
Volume39
Issue number2
StatePublished - Jan 1 1993

    Fingerprint

Keywords

  • Erythropoietin
  • Functional ability
  • Muscle strength
  • Quality of life

ASJC Scopus subject areas

  • Nephrology

Cite this

Guthrie, M., Gardenas, D., Eschbach, J. W., Haley, N. R., Robertson, H. T., & Evans, R. W. (1993). Effects of erythropoietin on strength and functional status of patients on hemodialysis. Clinical Nephrology, 39(2), 97-102.