Effects of cytochalasin B on division and calcium carbonate extrusion in a calcareous alga

Roy E. Weiss, Karl M. Wilbur

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Cytochalasin B (CB) (100 μg/ml) reversibly blocked cell division and cuased the formation of abnormal cytoplasmic bodies in the alga Cricosphaera carterae. Concentrations of 20 μg/ml and 40 μg/ml CB were without effects. In the presence of CB, calcified bodies (coccoliths) which form in Golgi vesicles and are normally extruded through the plasma membrane were not extruded and accumulated within the cell. CB appeared to alter the membranes of Golgi vesicles containing coccoliths. DMSO (10% v v), the solvent for CB, was without effect on cell division and coccolith extrusion. A concentration of 20% v v DMSO inhibited cell division irreversibly.

Original languageEnglish (US)
Pages (from-to)47-54
Number of pages8
JournalExperimental Cell Research
Volume112
Issue number1
DOIs
StatePublished - Mar 1 1978
Externally publishedYes

ASJC Scopus subject areas

  • Cell Biology

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