Abstract
Bleomycin treated mouse L 929 fibroblasts are large in size and often appear multinucleated. Quantitative cytochemical studies show that these cells have an increased content of DNA and total proteins (dry mass) per cell. The increased accumulation of DNA and protein content (4-8C or more) is compatible with and may well be related to the bleomycin induced inhibition of cell division and the resulting endoreduplication.
| Original language | English |
|---|---|
| Pages (from-to) | 1873-1877 |
| Number of pages | 5 |
| Journal | Cancer |
| Volume | 34 |
| Issue number | 6 |
| State | Published - Dec 1 1974 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cancer Research
- Oncology
Cite this
Effects of bleomycin on cells in culture : a quantitative cytochemical study. / Desai, L. S.; Krishan, A.; Foley, G. E.
In: Cancer, Vol. 34, No. 6, 01.12.1974, p. 1873-1877.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effects of bleomycin on cells in culture
T2 - a quantitative cytochemical study
AU - Desai, L. S.
AU - Krishan, A.
AU - Foley, G. E.
PY - 1974/12/1
Y1 - 1974/12/1
N2 - Bleomycin treated mouse L 929 fibroblasts are large in size and often appear multinucleated. Quantitative cytochemical studies show that these cells have an increased content of DNA and total proteins (dry mass) per cell. The increased accumulation of DNA and protein content (4-8C or more) is compatible with and may well be related to the bleomycin induced inhibition of cell division and the resulting endoreduplication.
AB - Bleomycin treated mouse L 929 fibroblasts are large in size and often appear multinucleated. Quantitative cytochemical studies show that these cells have an increased content of DNA and total proteins (dry mass) per cell. The increased accumulation of DNA and protein content (4-8C or more) is compatible with and may well be related to the bleomycin induced inhibition of cell division and the resulting endoreduplication.
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UR - http://www.scopus.com/inward/citedby.url?scp=0016312316&partnerID=8YFLogxK
M3 - Article
C2 - 4140018
AN - SCOPUS:0016312316
VL - 34
SP - 1873
EP - 1877
JO - Cancer
JF - Cancer
SN - 0008-543X
IS - 6
ER -