Effects of bleomycin on cells in culture: a quantitative cytochemical study

L. S. Desai, A. Krishan, G. E. Foley

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Bleomycin treated mouse L 929 fibroblasts are large in size and often appear multinucleated. Quantitative cytochemical studies show that these cells have an increased content of DNA and total proteins (dry mass) per cell. The increased accumulation of DNA and protein content (4-8C or more) is compatible with and may well be related to the bleomycin induced inhibition of cell division and the resulting endoreduplication.

Original languageEnglish
Pages (from-to)1873-1877
Number of pages5
JournalCancer
Volume34
Issue number6
StatePublished - Dec 1 1974
Externally publishedYes

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Bleomycin
Cell Culture Techniques
Endoreduplication
DNA
Cell Division
Proteins
Fibroblasts

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Desai, L. S., Krishan, A., & Foley, G. E. (1974). Effects of bleomycin on cells in culture: a quantitative cytochemical study. Cancer, 34(6), 1873-1877.

Effects of bleomycin on cells in culture : a quantitative cytochemical study. / Desai, L. S.; Krishan, A.; Foley, G. E.

In: Cancer, Vol. 34, No. 6, 01.12.1974, p. 1873-1877.

Research output: Contribution to journalArticle

Desai, LS, Krishan, A & Foley, GE 1974, 'Effects of bleomycin on cells in culture: a quantitative cytochemical study', Cancer, vol. 34, no. 6, pp. 1873-1877.
Desai LS, Krishan A, Foley GE. Effects of bleomycin on cells in culture: a quantitative cytochemical study. Cancer. 1974 Dec 1;34(6):1873-1877.
Desai, L. S. ; Krishan, A. ; Foley, G. E. / Effects of bleomycin on cells in culture : a quantitative cytochemical study. In: Cancer. 1974 ; Vol. 34, No. 6. pp. 1873-1877.
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