Effects of aortic valve replacement on the severity of mitral regurgitation

E. M. Cespedes, H. R. Aldrich, G. A. Lamas, A. S. Agatston, D. B. Williams, E. A. Traad, E. H. Lieberman

Research output: Contribution to journalArticle

Abstract

We determined the effect of aortic valve replacement for clinically significant aortic stenosis on the severity of mitral régurgitation. Intraoperative transesophageal echocardiography was performed in 65 patients before and after aortic valve replacement for aortic stenosis. Aortic stenosis was severe in 63% of the patients and moderate in 37%. Patients undergoing simultaneous mitral valve replacement for severe mitral régurgitation or mitral stenosis were excluded. There were 37 men and 28 women with a mean age of 73.9 ±1.1 years. The severity of mitral régurgitation was graded from 0 to 4 as determined by color flow Doppler and pulmonary vein flow. Mitral régurgitation was noted in 66% of patients undergoing aortic valve replacement for aortic stenosis. Immediately after aortic valve replacement, transesophageal echocardiography demonstrated decreased severity of mitral régurgitation by one grade in 55% and by two grades in 2% of the patients. Thirty six percent of the patients had no change in the severity of the mitral régurgitation and 7% had an increase of one grade. This reduction in mitral régurgitation was significant (p=0.0045, Wilcoxon Signed Ranks test). Conclusion: Patients with mild to moderate mitral régurgitation undergoing aortic valve replacement for aortic stenosis tend to show reduction in the severity of mitral régurgitation by approximately one grade.

Original languageEnglish (US)
Pages (from-to)209a
JournalJournal of Investigative Medicine
Volume44
Issue number3
StatePublished - Jan 1 1996

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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    Cespedes, E. M., Aldrich, H. R., Lamas, G. A., Agatston, A. S., Williams, D. B., Traad, E. A., & Lieberman, E. H. (1996). Effects of aortic valve replacement on the severity of mitral regurgitation. Journal of Investigative Medicine, 44(3), 209a.