Effects of acute and chronic waterborne lead exposure on the swimming performance and aerobic scope of fathead minnows (Pimephales promelas)

Edward M. Mager, Martin Grosell

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19 Citations (Scopus)

Abstract

Fathead minnows were subjected to an incremental velocity test using swim tunnel respirometry for the analysis of aerobic scope and swimming performance, as critical aerobic swim speed (Ucrit), following chronic exposures (33-57 d) to 0.9 ± 0.4, 157 ± 18 or 689 ± 66 nmol L - 1 Pb and an acute exposure (24 h) to 672 ± 35 nmol L - 1 Pb (mean ± SEM). Assessment of Pb-induced anemia and neurological impairment were evaluated by blood hemoglobin (Hb) concentrations and a cost of transport (COT) analysis, respectively. Fish from the acute 672 ± 35 nmol L- 1 Pb (24.4 ± 1.2 BL s- 1) and chronic 689 ± 66 nmol L- 1 Pb (24.6 ± 0.9 BL s - 1) treatments exhibited reduced Ucrits compared to control fish (27.6 ± 0.8 BL s- 1). Aerobic scope was reduced by acute Pb exposure (8.6 ± 2.6 μmol O2 g- 1 h- 1 vs. 22.6 ± 3.8 μmol O2 g- 1 h- 1 from controls) owing to a decrease in maximum oxygen consumption rate (38.8 ± 0.8 μmol O2 g- 1 h- 1 vs. 54.0 ± 4.2 μmol O2 g- 1 h- 1 from controls). However, no effect on aerobic scope was observed with fish chronically exposed to Pb. Significant differences were not observed for Hb concentrations or COT. These findings suggest that the impaired swimming performances arising from acute and chronic Pb exposures reflect different mechanisms of toxicity.

Original languageEnglish
Pages (from-to)7-13
Number of pages7
JournalComparative Biochemistry and Physiology - C Toxicology and Pharmacology
Volume154
Issue number1
DOIs
StatePublished - Jun 1 2011

Fingerprint

Cyprinidae
Fish
Fishes
Hemoglobins
Costs and Cost Analysis
Oxygen Consumption
Toxicity
Costs
Anemia
Tunnels
Blood
Oxygen
Scanning electron microscopy
Lead
Swimming

Keywords

  • Anemia
  • Cost of transport
  • Hemoglobin
  • Swim tunnel respirometry
  • Teleost
  • U

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology
  • Physiology
  • Health, Toxicology and Mutagenesis
  • Toxicology

Cite this

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abstract = "Fathead minnows were subjected to an incremental velocity test using swim tunnel respirometry for the analysis of aerobic scope and swimming performance, as critical aerobic swim speed (Ucrit), following chronic exposures (33-57 d) to 0.9 ± 0.4, 157 ± 18 or 689 ± 66 nmol L - 1 Pb and an acute exposure (24 h) to 672 ± 35 nmol L - 1 Pb (mean ± SEM). Assessment of Pb-induced anemia and neurological impairment were evaluated by blood hemoglobin (Hb) concentrations and a cost of transport (COT) analysis, respectively. Fish from the acute 672 ± 35 nmol L- 1 Pb (24.4 ± 1.2 BL s- 1) and chronic 689 ± 66 nmol L- 1 Pb (24.6 ± 0.9 BL s - 1) treatments exhibited reduced Ucrits compared to control fish (27.6 ± 0.8 BL s- 1). Aerobic scope was reduced by acute Pb exposure (8.6 ± 2.6 μmol O2 g- 1 h- 1 vs. 22.6 ± 3.8 μmol O2 g- 1 h- 1 from controls) owing to a decrease in maximum oxygen consumption rate (38.8 ± 0.8 μmol O2 g- 1 h- 1 vs. 54.0 ± 4.2 μmol O2 g- 1 h- 1 from controls). However, no effect on aerobic scope was observed with fish chronically exposed to Pb. Significant differences were not observed for Hb concentrations or COT. These findings suggest that the impaired swimming performances arising from acute and chronic Pb exposures reflect different mechanisms of toxicity.",
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