Effects of β-/Tyr9/melanotropin-/9-18/ on apomorphine-induced stereotyped cage-climbing and on striatal dopamine release in mice. Comparative studies with amphetamine

László Vécsei; Gyula Telegdy; Andrew V. Schally; David H. Coy

doi:10.1016/0143-4179(82)90004-X

Effects of β-/Tyr⁹/melanotropin-/9-18/ on apomorphine-induced stereotyped cage-climbing and on striatal dopamine release in mice. Comparative studies with amphetamine

László Vécsei, Gyula Telegdy, Andrew V. Schally, David H. Coy

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

β-/Tyr⁹/melanotropin-/9-18/ significantly increased apomorphine-induced cage-climbing, while only a tendency towards an increase was observed after supersensitization with haloperidol. Amphetamine also enhanced apomorphine-induced climbing behavior. The peptide showed only a tendency to increase dopamine release from striatal slices, while amphetamine elevated this significantly. The results suggest that the striatal dopamine system is involved in the behavioral action of β-/Tyr⁹/melanotropin-/9-18/.

Original language	English (US)
Pages (from-to)	91-96
Number of pages	6
Journal	Neuropeptides
Volume	3
Issue number	2
DOIs	https://doi.org/10.1016/0143-4179(82)90004-X
State	Published - Dec 1982
Externally published	Yes

ASJC Scopus subject areas

Endocrinology
Neurology
Endocrine and Autonomic Systems
Cellular and Molecular Neuroscience

Access to Document

10.1016/0143-4179(82)90004-X

Fingerprint Dive into the research topics of 'Effects of β-/Tyr<sup>9</sup>/melanotropin-/9-18/ on apomorphine-induced stereotyped cage-climbing and on striatal dopamine release in mice. Comparative studies with amphetamine'. Together they form a unique fingerprint.

Cite this

@article{c49bc35d28474c3788ad34680cd0f72f,

title = "Effects of β-/Tyr9/melanotropin-/9-18/ on apomorphine-induced stereotyped cage-climbing and on striatal dopamine release in mice. Comparative studies with amphetamine",

abstract = "β-/Tyr9/melanotropin-/9-18/ significantly increased apomorphine-induced cage-climbing, while only a tendency towards an increase was observed after supersensitization with haloperidol. Amphetamine also enhanced apomorphine-induced climbing behavior. The peptide showed only a tendency to increase dopamine release from striatal slices, while amphetamine elevated this significantly. The results suggest that the striatal dopamine system is involved in the behavioral action of β-/Tyr9/melanotropin-/9-18/.",

author = "L{\'a}szl{\'o} V{\'e}csei and Gyula Telegdy and Schally, {Andrew V.} and Coy, {David H.}",

year = "1982",

month = dec,

doi = "10.1016/0143-4179(82)90004-X",

language = "English (US)",

volume = "3",

pages = "91--96",

journal = "Neuropeptides",

issn = "0143-4179",

publisher = "Churchill Livingstone",

number = "2",

}

TY - JOUR

T1 - Effects of β-/Tyr9/melanotropin-/9-18/ on apomorphine-induced stereotyped cage-climbing and on striatal dopamine release in mice. Comparative studies with amphetamine

AU - Vécsei, László

AU - Telegdy, Gyula

AU - Schally, Andrew V.

AU - Coy, David H.

PY - 1982/12

Y1 - 1982/12

N2 - β-/Tyr9/melanotropin-/9-18/ significantly increased apomorphine-induced cage-climbing, while only a tendency towards an increase was observed after supersensitization with haloperidol. Amphetamine also enhanced apomorphine-induced climbing behavior. The peptide showed only a tendency to increase dopamine release from striatal slices, while amphetamine elevated this significantly. The results suggest that the striatal dopamine system is involved in the behavioral action of β-/Tyr9/melanotropin-/9-18/.

AB - β-/Tyr9/melanotropin-/9-18/ significantly increased apomorphine-induced cage-climbing, while only a tendency towards an increase was observed after supersensitization with haloperidol. Amphetamine also enhanced apomorphine-induced climbing behavior. The peptide showed only a tendency to increase dopamine release from striatal slices, while amphetamine elevated this significantly. The results suggest that the striatal dopamine system is involved in the behavioral action of β-/Tyr9/melanotropin-/9-18/.

UR - http://www.scopus.com/inward/record.url?scp=0020334405&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020334405&partnerID=8YFLogxK

U2 - 10.1016/0143-4179(82)90004-X

DO - 10.1016/0143-4179(82)90004-X

M3 - Article

C2 - 6891751

AN - SCOPUS:0020334405

VL - 3

SP - 91

EP - 96

JO - Neuropeptides

JF - Neuropeptides

SN - 0143-4179

IS - 2