Abstract
β-/Tyr9/melanotropin-/9-18/ significantly increased apomorphine-induced cage-climbing, while only a tendency towards an increase was observed after supersensitization with haloperidol. Amphetamine also enhanced apomorphine-induced climbing behavior. The peptide showed only a tendency to increase dopamine release from striatal slices, while amphetamine elevated this significantly. The results suggest that the striatal dopamine system is involved in the behavioral action of β-/Tyr9/melanotropin-/9-18/.
Original language | English (US) |
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Pages (from-to) | 91-96 |
Number of pages | 6 |
Journal | Neuropeptides |
Volume | 3 |
Issue number | 2 |
DOIs | |
State | Published - Dec 1982 |
Externally published | Yes |
ASJC Scopus subject areas
- Endocrinology
- Neurology
- Endocrine and Autonomic Systems
- Cellular and Molecular Neuroscience