Effectiveness of Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature

Jessica Cervantes, Marina Perper, Lulu L. Wong, Ariel E. Eber, Alexandra C.Villasante Fricke, Tongyu Cao Wikramanayake, Joaquin J. Jimenez

Research output: Contribution to journalReview article

13 Scopus citations

Abstract

Androgenetic alopecia (AGA) is a hair loss disorder affecting 80% of men and 50% of women throughout their lifetime. Therapies for AGA are limited and there is no cure. There is a high demand for hair restoration. Platelet-rich plasma (PRP), a treatment modality shown to promote wound healing, has also been explored as a treatment for AGA. This literature review was conducted to assess the effectiveness of PRP treatment for AGA. Twelve studies conducted from 2011 to 2017 were evaluated and summarized by study characteristics, mode of preparation, and treatment protocols. A total of 295 subjects were given PRP or control treatment in these studies, and evaluated for terminal hair density, hair quality, anagen/telogen hair ratio, keratinocyte proliferation, blood vessel density, etc. Some studies also provided subject self-assessment reports. Most of the studies reviewed showed effectiveness of PRP in increasing terminal hair density/diameter. Additional investigations are needed to determine the optimal treatment regimen for high efficacy of PRP in AGA.

Original languageEnglish (US)
Pages (from-to)1-11
Number of pages11
JournalSkin Appendage Disorders
Volume4
Issue number1
DOIs
StatePublished - Jan 1 2018

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Keywords

  • Androgenetic alopecia
  • Androgenic alopecia
  • Growth factors
  • Hair disorder
  • Hair follicle
  • Hair growth
  • Platelet-rich plasma

ASJC Scopus subject areas

  • Dermatology

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