Effectiveness of Holmium laser-assisted coronary angioplasty

Eduardo J. de Marchena, Stephen M. Mallon, William D. Knopf, Kirk Parr, Jeffrey W. Moses, Douglas Murphy-Chutorian, Robert J. Myerburg, Holmium Laser Coronary Registry The Holmium Laser Coronary Registry

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


The efficacy of Holmium laser-assisted angioplasty was studied in 365 narrowings in 331 consecutive patients with coronary artery disease. Clinical indications for study were unstable angina pectoris in 140 patients (42%), stable angina in 136 patients (41%), postmyocardial infarction angina in 35 patients (10.5%), silent myocardial ischemia in 11 patients (3%), acute myocardial infarction in 1 patient (0.3%) and undefined in 8 patients (2%). Coronary morphology characteristics by Multivessel Angioplasty Prognosis Study group criteria were type A in 12.6%, type B1 in 34.2%, type B2 in 27.4% and type C in 25.4%. The laser successfully crossed the total length of the narrowing in 85.2%. Procedural success was 94.2%. Laser alone reduced mean percent luminal narrowing from 88 ± 11% to 57 ± 22%. Subsequent balloon angioplasty further reduced the mean luminal narrowing to 23 ± 18%. Major complication rate was 2.7% (death 0.3%, Q-wave myocardial infarction 0.5%, and emergent bypass surgery 2.7%). Six-month angiographic restenosis (>50% stenosis) rate was 44%.

Original languageEnglish (US)
Pages (from-to)117-121
Number of pages5
JournalThe American Journal of Cardiology
Issue number2
StatePublished - Jan 15 1994

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Effectiveness of Holmium laser-assisted coronary angioplasty'. Together they form a unique fingerprint.

Cite this