Abstract
The efficacy of Holmium laser-assisted angioplasty was studied in 365 narrowings in 331 consecutive patients with coronary artery disease. Clinical indications for study were unstable angina pectoris in 140 patients (42%), stable angina in 136 patients (41%), postmyocardial infarction angina in 35 patients (10.5%), silent myocardial ischemia in 11 patients (3%), acute myocardial infarction in 1 patient (0.3%) and undefined in 8 patients (2%). Coronary morphology characteristics by Multivessel Angioplasty Prognosis Study group criteria were type A in 12.6%, type B1 in 34.2%, type B2 in 27.4% and type C in 25.4%. The laser successfully crossed the total length of the narrowing in 85.2%. Procedural success was 94.2%. Laser alone reduced mean percent luminal narrowing from 88 ± 11% to 57 ± 22%. Subsequent balloon angioplasty further reduced the mean luminal narrowing to 23 ± 18%. Major complication rate was 2.7% (death 0.3%, Q-wave myocardial infarction 0.5%, and emergent bypass surgery 2.7%). Six-month angiographic restenosis (>50% stenosis) rate was 44%.
| Original language | English |
|---|---|
| Pages (from-to) | 117-121 |
| Number of pages | 5 |
| Journal | The American journal of cardiology |
| Volume | 73 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 15 1994 |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Effectiveness of Holmium laser-assisted coronary angioplasty. / De Marchena, Eduardo; Mallon, Stephen M.; Knopf, William D.; Parr, Kirk; Moses, Jeffrey W.; Murphy-Chutorian, Douglas; Myerburg, Robert J; The Holmium Laser Coronary Registry, Holmium Laser Coronary Registry.
In: The American journal of cardiology, Vol. 73, No. 2, 15.01.1994, p. 117-121.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effectiveness of Holmium laser-assisted coronary angioplasty
AU - De Marchena, Eduardo
AU - Mallon, Stephen M.
AU - Knopf, William D.
AU - Parr, Kirk
AU - Moses, Jeffrey W.
AU - Murphy-Chutorian, Douglas
AU - Myerburg, Robert J
AU - The Holmium Laser Coronary Registry, Holmium Laser Coronary Registry
PY - 1994/1/15
Y1 - 1994/1/15
N2 - The efficacy of Holmium laser-assisted angioplasty was studied in 365 narrowings in 331 consecutive patients with coronary artery disease. Clinical indications for study were unstable angina pectoris in 140 patients (42%), stable angina in 136 patients (41%), postmyocardial infarction angina in 35 patients (10.5%), silent myocardial ischemia in 11 patients (3%), acute myocardial infarction in 1 patient (0.3%) and undefined in 8 patients (2%). Coronary morphology characteristics by Multivessel Angioplasty Prognosis Study group criteria were type A in 12.6%, type B1 in 34.2%, type B2 in 27.4% and type C in 25.4%. The laser successfully crossed the total length of the narrowing in 85.2%. Procedural success was 94.2%. Laser alone reduced mean percent luminal narrowing from 88 ± 11% to 57 ± 22%. Subsequent balloon angioplasty further reduced the mean luminal narrowing to 23 ± 18%. Major complication rate was 2.7% (death 0.3%, Q-wave myocardial infarction 0.5%, and emergent bypass surgery 2.7%). Six-month angiographic restenosis (>50% stenosis) rate was 44%.
AB - The efficacy of Holmium laser-assisted angioplasty was studied in 365 narrowings in 331 consecutive patients with coronary artery disease. Clinical indications for study were unstable angina pectoris in 140 patients (42%), stable angina in 136 patients (41%), postmyocardial infarction angina in 35 patients (10.5%), silent myocardial ischemia in 11 patients (3%), acute myocardial infarction in 1 patient (0.3%) and undefined in 8 patients (2%). Coronary morphology characteristics by Multivessel Angioplasty Prognosis Study group criteria were type A in 12.6%, type B1 in 34.2%, type B2 in 27.4% and type C in 25.4%. The laser successfully crossed the total length of the narrowing in 85.2%. Procedural success was 94.2%. Laser alone reduced mean percent luminal narrowing from 88 ± 11% to 57 ± 22%. Subsequent balloon angioplasty further reduced the mean luminal narrowing to 23 ± 18%. Major complication rate was 2.7% (death 0.3%, Q-wave myocardial infarction 0.5%, and emergent bypass surgery 2.7%). Six-month angiographic restenosis (>50% stenosis) rate was 44%.
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U2 - 10.1016/0002-9149(94)90200-3
DO - 10.1016/0002-9149(94)90200-3
M3 - Article
C2 - 8296731
AN - SCOPUS:0028012713
VL - 73
SP - 117
EP - 121
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 2
ER -