Effectiveness of Holmium laser-assisted coronary angioplasty

Eduardo De Marchena, Stephen M. Mallon, William D. Knopf, Kirk Parr, Jeffrey W. Moses, Douglas Murphy-Chutorian, Robert J Myerburg, Holmium Laser Coronary Registry The Holmium Laser Coronary Registry

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Abstract

The efficacy of Holmium laser-assisted angioplasty was studied in 365 narrowings in 331 consecutive patients with coronary artery disease. Clinical indications for study were unstable angina pectoris in 140 patients (42%), stable angina in 136 patients (41%), postmyocardial infarction angina in 35 patients (10.5%), silent myocardial ischemia in 11 patients (3%), acute myocardial infarction in 1 patient (0.3%) and undefined in 8 patients (2%). Coronary morphology characteristics by Multivessel Angioplasty Prognosis Study group criteria were type A in 12.6%, type B1 in 34.2%, type B2 in 27.4% and type C in 25.4%. The laser successfully crossed the total length of the narrowing in 85.2%. Procedural success was 94.2%. Laser alone reduced mean percent luminal narrowing from 88 ± 11% to 57 ± 22%. Subsequent balloon angioplasty further reduced the mean luminal narrowing to 23 ± 18%. Major complication rate was 2.7% (death 0.3%, Q-wave myocardial infarction 0.5%, and emergent bypass surgery 2.7%). Six-month angiographic restenosis (>50% stenosis) rate was 44%.

Original languageEnglish
Pages (from-to)117-121
Number of pages5
JournalThe American journal of cardiology
Volume73
Issue number2
DOIs
StatePublished - Jan 15 1994

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Laser-Assisted Balloon Angioplasty
Solid-State Lasers
Lasers
Myocardial Infarction
Balloon Angioplasty
Stable Angina
Unstable Angina
Angioplasty
Infarction
Myocardial Ischemia
Coronary Artery Disease
Pathologic Constriction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

De Marchena, E., Mallon, S. M., Knopf, W. D., Parr, K., Moses, J. W., Murphy-Chutorian, D., ... The Holmium Laser Coronary Registry, H. L. C. R. (1994). Effectiveness of Holmium laser-assisted coronary angioplasty. The American journal of cardiology, 73(2), 117-121. https://doi.org/10.1016/0002-9149(94)90200-3

Effectiveness of Holmium laser-assisted coronary angioplasty. / De Marchena, Eduardo; Mallon, Stephen M.; Knopf, William D.; Parr, Kirk; Moses, Jeffrey W.; Murphy-Chutorian, Douglas; Myerburg, Robert J; The Holmium Laser Coronary Registry, Holmium Laser Coronary Registry.

In: The American journal of cardiology, Vol. 73, No. 2, 15.01.1994, p. 117-121.

Research output: Contribution to journalArticle

De Marchena, E, Mallon, SM, Knopf, WD, Parr, K, Moses, JW, Murphy-Chutorian, D, Myerburg, RJ & The Holmium Laser Coronary Registry, HLCR 1994, 'Effectiveness of Holmium laser-assisted coronary angioplasty', The American journal of cardiology, vol. 73, no. 2, pp. 117-121. https://doi.org/10.1016/0002-9149(94)90200-3
De Marchena, Eduardo ; Mallon, Stephen M. ; Knopf, William D. ; Parr, Kirk ; Moses, Jeffrey W. ; Murphy-Chutorian, Douglas ; Myerburg, Robert J ; The Holmium Laser Coronary Registry, Holmium Laser Coronary Registry. / Effectiveness of Holmium laser-assisted coronary angioplasty. In: The American journal of cardiology. 1994 ; Vol. 73, No. 2. pp. 117-121.
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