Abstract
T-cell subpopulations and their function were studied in asthmatic children with or without theophylline therapy. A decreased proportion and function of theophylline-sensitive T-suppressor cells was found in fresh peripheral blood of asthmatic children. Following peripheral blood mononuclear cells (PBMC) incubation in theophylline-free medium, the proportion of theophylline-sensitive T-cells in asthmatic children treated with theophylline was elevated to normal values. However, their suppressive effect on control lymphocyte proliferation was unchanged.
Original language | English (US) |
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Pages (from-to) | 453-457 |
Number of pages | 5 |
Journal | Allergy |
Volume | 40 |
Issue number | 6 |
DOIs | |
State | Published - Aug 1985 |
Keywords
- asthma
- suppressor T‐cells
- theophylline. Accepted for publication 15 March 1985
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology