Abstract
Somatostatin (SS-14; growth hormone-release inhibiting hormone) was infused into eight patients with non-toxic sporadic goiter and into eleven normal control subjects. Each patient was given 150 μg of somatostatin as an intravenous bolus and 350 μg by infusion over a period of 60 minutes. Somatostatin did not lower the basal TSH levels as compared to the pre-infusion levels in this type of goiter, but produced a decrease in the TSH response to TRH during and after the infusion.
Original language | English (US) |
---|---|
Pages (from-to) | 627-631 |
Number of pages | 5 |
Journal | Hormone and Metabolic Research |
Volume | 22 |
Issue number | 12 |
DOIs | |
State | Published - 1990 |
Externally published | Yes |
Keywords
- goiter
- somatostatin
- TRH
- TSH
ASJC Scopus subject areas
- Biochemistry
- Endocrinology