Abstract
The effect of somatostatin on the spontaneous proliferation of mouse spleen lymphocytes was investigated invitro. The rate of 3H-thymidine incorporation was used as an index of lymphocyte proliferation. Somatostatin in a concentration of 10-7M enhanced the lymphocyte proliferation and abolished the antiproliferative effect of rat hypothalamic extract. Lower concentrations of somatostatin slightly decreased the lymphocyte DNA synthesis.
Original language | English (US) |
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Pages (from-to) | 52-55 |
Number of pages | 4 |
Journal | Biochemical and biophysical research communications |
Volume | 129 |
Issue number | 1 |
DOIs | |
State | Published - May 31 1985 |
Externally published | Yes |
ASJC Scopus subject areas
- Biophysics
- Biochemistry
- Molecular Biology
- Cell Biology