Abstract
The effect of somatostatin on the spontaneous proliferation of mouse spleen lymphocytes was investigated invitro. The rate of 3H-thymidine incorporation was used as an index of lymphocyte proliferation. Somatostatin in a concentration of 10-7M enhanced the lymphocyte proliferation and abolished the antiproliferative effect of rat hypothalamic extract. Lower concentrations of somatostatin slightly decreased the lymphocyte DNA synthesis.
| Original language | English |
|---|---|
| Pages (from-to) | 52-55 |
| Number of pages | 4 |
| Journal | Biochemical and Biophysical Research Communications |
| Volume | 129 |
| Issue number | 1 |
| DOIs | |
| State | Published - May 31 1985 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Biochemistry
- Biophysics
- Molecular Biology
Cite this
Effect of somatostatin on the proliferation of mouse spleen lymphocytes in, vitro. / Pawlikowski, Marek; Stepien, Henryk; Kunert-Radek, Jolanta; Schally, Andrew V.
In: Biochemical and Biophysical Research Communications, Vol. 129, No. 1, 31.05.1985, p. 52-55.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effect of somatostatin on the proliferation of mouse spleen lymphocytes in, vitro
AU - Pawlikowski, Marek
AU - Stepien, Henryk
AU - Kunert-Radek, Jolanta
AU - Schally, Andrew V
PY - 1985/5/31
Y1 - 1985/5/31
N2 - The effect of somatostatin on the spontaneous proliferation of mouse spleen lymphocytes was investigated invitro. The rate of 3H-thymidine incorporation was used as an index of lymphocyte proliferation. Somatostatin in a concentration of 10-7M enhanced the lymphocyte proliferation and abolished the antiproliferative effect of rat hypothalamic extract. Lower concentrations of somatostatin slightly decreased the lymphocyte DNA synthesis.
AB - The effect of somatostatin on the spontaneous proliferation of mouse spleen lymphocytes was investigated invitro. The rate of 3H-thymidine incorporation was used as an index of lymphocyte proliferation. Somatostatin in a concentration of 10-7M enhanced the lymphocyte proliferation and abolished the antiproliferative effect of rat hypothalamic extract. Lower concentrations of somatostatin slightly decreased the lymphocyte DNA synthesis.
UR - http://www.scopus.com/inward/record.url?scp=0021795884&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021795884&partnerID=8YFLogxK
U2 - 10.1016/0006-291X(85)91401-9
DO - 10.1016/0006-291X(85)91401-9
M3 - Article
C2 - 2860904
AN - SCOPUS:0021795884
VL - 129
SP - 52
EP - 55
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
SN - 0006-291X
IS - 1
ER -