Abstract
The effect of somatostatin on the spontaneous proliferation of mouse spleen lymphocytes was investigated invitro. The rate of 3H-thymidine incorporation was used as an index of lymphocyte proliferation. Somatostatin in a concentration of 10-7M enhanced the lymphocyte proliferation and abolished the antiproliferative effect of rat hypothalamic extract. Lower concentrations of somatostatin slightly decreased the lymphocyte DNA synthesis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 52-55 |
| Number of pages | 4 |
| Journal | Biochemical and biophysical research communications |
| Volume | 129 |
| Issue number | 1 |
| DOIs | |
| State | Published - May 31 1985 |
| Externally published | Yes |
ASJC Scopus subject areas
- Biophysics
- Biochemistry
- Molecular Biology
- Cell Biology
Fingerprint Dive into the research topics of 'Effect of somatostatin on the proliferation of mouse spleen lymphocytes in, vitro'. Together they form a unique fingerprint.
Cite this
Pawlikowski, M., Stepien, H., Kunert-Radek, J., & Schally, A. V. (1985). Effect of somatostatin on the proliferation of mouse spleen lymphocytes in, vitro. Biochemical and biophysical research communications, 129(1), 52-55. https://doi.org/10.1016/0006-291X(85)91401-9