Abstract
Irradiated wounds are characterized by a slow healing process. Insulin-like growth factor-1 (IGF-1), a somatomedin C, has been shown in previous studies to stimulate collagen synthesis and bony repair. The purpose of this investigation is to evaluate the potential beneficial effects of recombinant IGF-1 in the healing of critical size calvarial defects in previously irradiated adult male Sprague-Dawley Rats.
| Original language | English |
|---|---|
| Pages (from-to) | 138-141 |
| Number of pages | 4 |
| Journal | Journal of Craniofacial Surgery |
| Volume | 9 |
| Issue number | 2 |
| State | Published - Mar 1 1998 |
Fingerprint
Keywords
- Critical size calvarial bone defects
- Insulin-like growth factor type I
ASJC Scopus subject areas
- Surgery
Cite this
Effect of insulin-like growth factor type I on critical size calvarial bone defects in irradiated rats. / Thaller, Seth; Salzhauer, Michael A.; Rubinstein, Adam J.; Thion, Alain; Tesluk, Henry.
In: Journal of Craniofacial Surgery, Vol. 9, No. 2, 01.03.1998, p. 138-141.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effect of insulin-like growth factor type I on critical size calvarial bone defects in irradiated rats
AU - Thaller, Seth
AU - Salzhauer, Michael A.
AU - Rubinstein, Adam J.
AU - Thion, Alain
AU - Tesluk, Henry
PY - 1998/3/1
Y1 - 1998/3/1
N2 - Irradiated wounds are characterized by a slow healing process. Insulin-like growth factor-1 (IGF-1), a somatomedin C, has been shown in previous studies to stimulate collagen synthesis and bony repair. The purpose of this investigation is to evaluate the potential beneficial effects of recombinant IGF-1 in the healing of critical size calvarial defects in previously irradiated adult male Sprague-Dawley Rats.
AB - Irradiated wounds are characterized by a slow healing process. Insulin-like growth factor-1 (IGF-1), a somatomedin C, has been shown in previous studies to stimulate collagen synthesis and bony repair. The purpose of this investigation is to evaluate the potential beneficial effects of recombinant IGF-1 in the healing of critical size calvarial defects in previously irradiated adult male Sprague-Dawley Rats.
KW - Critical size calvarial bone defects
KW - Insulin-like growth factor type I
UR - http://www.scopus.com/inward/record.url?scp=0031944417&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031944417&partnerID=8YFLogxK
M3 - Article
C2 - 9586542
AN - SCOPUS:0031944417
VL - 9
SP - 138
EP - 141
JO - Journal of Craniofacial Surgery
JF - Journal of Craniofacial Surgery
SN - 1049-2275
IS - 2
ER -