Abstract
Irradiated wounds are characterized by a slow healing process. Insulin-like growth factor-1 (IGF-1), a somatomedin C, has been shown in previous studies to stimulate collagen synthesis and bony repair. The purpose of this investigation is to evaluate the potential beneficial effects of recombinant IGF-1 in the healing of critical size calvarial defects in previously irradiated adult male Sprague-Dawley Rats.
Original language | English (US) |
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Pages (from-to) | 138-141 |
Number of pages | 4 |
Journal | Journal of Craniofacial Surgery |
Volume | 9 |
Issue number | 2 |
DOIs | |
State | Published - Mar 1998 |
Keywords
- Critical size calvarial bone defects
- Insulin-like growth factor type I
ASJC Scopus subject areas
- Surgery