Abstract
Irradiated wounds are characterized by a slow healing process. Insulin-like growth factor-1 (IGF-1), a somatomedin C, has been shown in previous studies to stimulate collagen synthesis and bony repair. The purpose of this investigation is to evaluate the potential beneficial effects of recombinant IGF-1 in the healing of critical size calvarial defects in previously irradiated adult male Sprague-Dawley Rats.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 138-141 |
| Number of pages | 4 |
| Journal | Journal of Craniofacial Surgery |
| Volume | 9 |
| Issue number | 2 |
| DOIs | |
| State | Published - Mar 1998 |
Keywords
- Critical size calvarial bone defects
- Insulin-like growth factor type I
ASJC Scopus subject areas
- Surgery
Fingerprint Dive into the research topics of 'Effect of insulin-like growth factor type I on critical size calvarial bone defects in irradiated rats'. Together they form a unique fingerprint.
Cite this
Thaller, S. R., Salzhauer, M. A., Rubinstein, A. J., Thion, A., & Tesluk, H. (1998). Effect of insulin-like growth factor type I on critical size calvarial bone defects in irradiated rats. Journal of Craniofacial Surgery, 9(2), 138-141. https://doi.org/10.1097/00001665-199803000-00010