Effect of hypercapnia on fluid filtration rate during forward and reverse perfusion of isolated rabbit lungs

R. Sanchez de Leon, I. Brajkovich, J. Zabner, R. Martinez-Ruiz, S. Angeli

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Fluid filtration rate (FFR) was measured under predominantly zone-three conditions in isolated rabbit lung perfused at constant flow. During forward and reverse perfusion, alveolar hypercapnia significantly increased mean pulmonary artery pressure but did not change FFR. We conclude that the pulmonary vasoconstriction induced by alveolar hypercapnia occurs on both arterial and venular sides of the pulmonary circulation.

Original languageEnglish (US)
Pages (from-to)285-287
Number of pages3
JournalCritical care medicine
Volume14
Issue number4
DOIs
StatePublished - 1986
Externally publishedYes

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Fingerprint Dive into the research topics of 'Effect of hypercapnia on fluid filtration rate during forward and reverse perfusion of isolated rabbit lungs'. Together they form a unique fingerprint.

Cite this