Abstract
The effects of pretreatment with estradiol benzoate on the pituitary release of LH and FSH in response to LH RH were investigated in male rats at various time intervals after castration. In oil treated control rats, LH RH brought about a significant increase in serum LH at all the periods after castration. One day after castration, pretreatment with estradiol significantly inhibited the response to LH RH, as observed in normal male rats. One week after castration estradiol induced a greater response to LH RH than observed in oil treated control rats, although the difference was not significant. One and two months after castration, estradiol significantly increased the response to LH RH.
| Original language | English |
|---|---|
| Pages (from-to) | 1164-1167 |
| Number of pages | 4 |
| Journal | Proceedings of the Society for Experimental Biology and Medicine |
| Volume | 143 |
| Issue number | 4 |
| State | Published - Dec 1 1973 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
Cite this
Effect of estradiol on the response to LH RH in male rats at different times after castration. / Debeljuk, L.; Arimura, A.; Schally, Andrew V.
In: Proceedings of the Society for Experimental Biology and Medicine, Vol. 143, No. 4, 01.12.1973, p. 1164-1167.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Effect of estradiol on the response to LH RH in male rats at different times after castration
AU - Debeljuk, L.
AU - Arimura, A.
AU - Schally, Andrew V
PY - 1973/12/1
Y1 - 1973/12/1
N2 - The effects of pretreatment with estradiol benzoate on the pituitary release of LH and FSH in response to LH RH were investigated in male rats at various time intervals after castration. In oil treated control rats, LH RH brought about a significant increase in serum LH at all the periods after castration. One day after castration, pretreatment with estradiol significantly inhibited the response to LH RH, as observed in normal male rats. One week after castration estradiol induced a greater response to LH RH than observed in oil treated control rats, although the difference was not significant. One and two months after castration, estradiol significantly increased the response to LH RH.
AB - The effects of pretreatment with estradiol benzoate on the pituitary release of LH and FSH in response to LH RH were investigated in male rats at various time intervals after castration. In oil treated control rats, LH RH brought about a significant increase in serum LH at all the periods after castration. One day after castration, pretreatment with estradiol significantly inhibited the response to LH RH, as observed in normal male rats. One week after castration estradiol induced a greater response to LH RH than observed in oil treated control rats, although the difference was not significant. One and two months after castration, estradiol significantly increased the response to LH RH.
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UR - http://www.scopus.com/inward/citedby.url?scp=0015868752&partnerID=8YFLogxK
M3 - Article
C2 - 4743696
AN - SCOPUS:0015868752
VL - 143
SP - 1164
EP - 1167
JO - Experimental Biology and Medicine
JF - Experimental Biology and Medicine
SN - 0037-9727
IS - 4
ER -