Effect of ergot alkaloids on serum prolactin in non-psychotic organic brain syndrome of the elderly

R. J. Gross, C. E. Eisdorfer, H. S. Schiller, G. Cox

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2 Scopus citations

Abstract

A compound of ergot alkaloids (Hydergine-Sandoz) or placebo was given to sixty elderly nursing home patients with non-psychotic organic brain syndrome. Subsequent to 12 weeks of treatment, the mean serum prolactin of the drug group was significantly lower than that of the placebo group. No correlation was found between changes in prolactin and changes in behavior using Sandoz Assessment of Clinical Status Rating Form-Geriatric. It may be that a higher dose of Hydergine with an accompanying greater drop in prolactin would be required to observe this effect.

Original languageEnglish
Pages (from-to)293-302
Number of pages10
JournalExperimental Aging Research
Volume5
Issue number4
StatePublished - Dec 1 1979
Externally publishedYes

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ASJC Scopus subject areas

  • Aging
  • Geriatrics and Gerontology
  • Psychology(all)

Cite this

Gross, R. J., Eisdorfer, C. E., Schiller, H. S., & Cox, G. (1979). Effect of ergot alkaloids on serum prolactin in non-psychotic organic brain syndrome of the elderly. Experimental Aging Research, 5(4), 293-302.