A compound of ergot alkaloids (Hydergine-Sandoz) or placebo was given to sixty elderly nursing home patients with non-psychotic organic brain syndrome. Subsequent to 12 weeks of treatment, the mean serum prolactin of the drug group was significantly lower than that of the placebo group. No correlation was found between changes in prolactin and changes in behavior using Sandoz Assessment of Clinical Status Rating Form-Geriatric. It may be that a higher dose of Hydergine with an accompanying greater drop in prolactin would be required to observe this effect.
ASJC Scopus subject areas
- Arts and Humanities (miscellaneous)
- Geriatrics and Gerontology