Abstract
In an earlier paper, we presented a simple model to describe the behavior of a microheterogeneous enzyme undergoing first-order deactivation. This report looks at the behavior of such a heterogeneous enzyme in fixed- and fluid-bed reactors. Our studies indicate that microheterogeneity does influence deactivation behavior even when present in small quantities. However, the models presented should be used with caution. For instance, a stabilizing effect as seen with microheterogeneity can be caused by other factors such as preparative/immobilization procedures, chemical effects, etc. Therefore, these models and the conclusions should be used only if physical evidence of microheterogeneity is seen in an enzyme sample.
Original language | English (US) |
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Pages (from-to) | 312-318 |
Number of pages | 7 |
Journal | Annals of the New York Academy of Sciences |
Volume | 542 |
Issue number | 1 |
DOIs | |
State | Published - Dec 1988 |
Externally published | Yes |
ASJC Scopus subject areas
- Neuroscience(all)
- Biochemistry, Genetics and Molecular Biology(all)
- History and Philosophy of Science