Effect of disc degeneration on streaming potential of human anulus fibrosus

W. Y. Gu, J. Rabin, W. M. Lai, B. A. Rawlins, V. C. Mow

Research output: Contribution to journalArticlepeer-review


The streaming potential responses of anulus fibrosus (AF) from human intervertebral discs to steady and sinusoidal (ie, dynamic) applied pressures were measured and analyzed. It was found that the streaming potential response was linear for non-degenerate AF specimens, and there was no phase lag. For degenerate AF specimens, the response was nonlinear. The magnitudes of the streaming potential response were significantly different between non-degenerate and degenerate AF specimens: non-degenerate = 5.38±0.88 mV/MPa; and degenerate = 4.41 ±0.99 mV/MPa. This phenomenon offers a possible way for detecting AF degeneration in vivo.

Original languageEnglish (US)
Pages (from-to)251-252
Number of pages2
JournalAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
StatePublished - Dec 1 1996
Externally publishedYes

ASJC Scopus subject areas

  • Engineering(all)

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