Effect of corticosteroids on survival of children with acquired immunodeficiency syndrome and Pneumocystis carinii -related respiratory failure

Gwenn E. McLaughlin, Satranjan S. Virdee, Charles L. Schleien, Bernard H. Holzman, Gwendolyn B. Scott

Research output: Contribution to journalArticle

47 Scopus citations


The medical records of patients with acquired immunodeficiency syndrome were reviewed to evaluate the effect of our adoption to the pediatric population of the National Institutes of Health recommendation for adjunctive corticosteroid therapy in adults with Pneumocystis carinii pneumonia. In 21 episodes of P. carinii-related respiratory failure, only adjunctive corticosteroids were associated with a significant improvement in survival to successful removal of the tracheal tube, from a historical rate of 11% to 91%. (J P EDIATR 1995;126:821-4).

Original languageEnglish (US)
Pages (from-to)821-824
Number of pages4
JournalThe Journal of Pediatrics
Issue number5
StatePublished - May 1995
Externally publishedYes


ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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