Effect of chlorophyll and aqueous extracts of Bacopa monniera and Valeriana wallichii on ischaemia and reperfusion-induced cerebral injury in mice

Ashish K. Rehni, Hardeep S. Pantlya, Richa Shri, Manjeet Singh

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Bilateral carotid artery occlusion followed by reperfusion produced significant cerebral infarction and impaired shortterm memory, motor co-ordination and lateral push response. Individual pretreatments with chlorophyll and aqueous extracts of B. monniera and V. wallichii markedly attenuated ischaemia-reperfusion induced cerebral injury in terms of decreased infarct size, increase in short-term memory, motor in coordination and lateral push response. The results suggest that chlorophyll and aqueous extracts of B. monniera and V. wallichii prevent ischaemia-reperfusion induced cerebral injury with comparable potency.

Original languageEnglish (US)
Pages (from-to)764-769
Number of pages6
JournalIndian Journal of Experimental Biology
Volume45
Issue number9
StatePublished - Sep 2007
Externally publishedYes

Keywords

  • Bacopa monniera
  • Cerebral injury
  • Chlorophyll
  • Valeriana wallichii

ASJC Scopus subject areas

  • Biotechnology
  • Molecular Biology
  • Cell Biology

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