Abstract
In Adriamycin-sensitive and -resistant P388 cells, coincubation with amphotericin B causes a marked increase in Adriamycin retention, as determined by laser flow cytometry. P388/S cells were generally more affected than were P388/R cells. Preincubation with amphotericin B had a greater effect on Adriamycin retention than did co- or postincubation. In splenocytes, bone marrow, and ascites from mice, enhanced Adriamycin retention was seen in all the tissues. However, bone marrow cells showed heterogeneous response, with some populations being more sensitive than others.
| Original language | English |
|---|---|
| Pages (from-to) | 4097-4102 |
| Number of pages | 6 |
| Journal | Cancer Research |
| Volume | 45 |
| Issue number | 9 |
| State | Published - Dec 1 1985 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cancer Research
- Oncology
Cite this
Krishan, A., Sauerteig, A., & Gordon, K. (1985). Effect of amphotericin B on adriamycin transport in P388 cells. Cancer Research, 45(9), 4097-4102.