Edrophonium test in Eaton-Lambert syndrome

Quantitative oculography

L. F. Dell'Osso, D. R. Ayyar, R. B. Daroff, L. A. Abel

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Accurate ocular motility recordings were made of the saccadic responses of five patients with Eaton-Lambert syndrome (ELS). It was found that, contrary to common belief, the ocular motor system is affected. The saccades of ELS patients mimicked those of patients with myasthenia gravis (MG). Both groups exhibited hypometria and multiple, closely spaced saccades. Two patients demonstrated both saccadic facilitation and positive edrophonium tests. The ELS patients had slow or normal saccadic velocities, not the 'super-fast' velocities found in patients with ocular MG.

Original languageEnglish
Pages (from-to)1157-1163
Number of pages7
JournalNeurology
Volume33
Issue number9
StatePublished - Jan 1 1983

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Lambert-Eaton Myasthenic Syndrome
Edrophonium
Saccades
Myasthenia Gravis

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Dell'Osso, L. F., Ayyar, D. R., Daroff, R. B., & Abel, L. A. (1983). Edrophonium test in Eaton-Lambert syndrome: Quantitative oculography. Neurology, 33(9), 1157-1163.

Edrophonium test in Eaton-Lambert syndrome : Quantitative oculography. / Dell'Osso, L. F.; Ayyar, D. R.; Daroff, R. B.; Abel, L. A.

In: Neurology, Vol. 33, No. 9, 01.01.1983, p. 1157-1163.

Research output: Contribution to journalArticle

Dell'Osso, LF, Ayyar, DR, Daroff, RB & Abel, LA 1983, 'Edrophonium test in Eaton-Lambert syndrome: Quantitative oculography', Neurology, vol. 33, no. 9, pp. 1157-1163.
Dell'Osso LF, Ayyar DR, Daroff RB, Abel LA. Edrophonium test in Eaton-Lambert syndrome: Quantitative oculography. Neurology. 1983 Jan 1;33(9):1157-1163.
Dell'Osso, L. F. ; Ayyar, D. R. ; Daroff, R. B. ; Abel, L. A. / Edrophonium test in Eaton-Lambert syndrome : Quantitative oculography. In: Neurology. 1983 ; Vol. 33, No. 9. pp. 1157-1163.
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