ECG-gated cardiac MDCT for detection of systolic anterior motion of mitral valve

Eduard Ghersin, Ivan Castellon, Jennifer E. Runco Therrien, Tanyanan Tanawuttiwat, Jonathan Lessick, Adam Checkver, Victor Soto

Research output: Contribution to journalArticle

Abstract

Objectives: Evaluating ECG-gated cardiac MDCT detection of systolic anterior motion of the mitral valve, in comparison to trans-thoracic echocardiography as a gold standard. Materials and methods: Study group included 83 consecutive patients (57 men; average age 56.1 years) evaluated with both retrospective ECG-gated cardiac MDCT and trans-thoracic echocardiography within an interval of 30 days. ECG-gated cardiac MDCT imaging was performed with retrospective ECG-gating using 64-slice and 128-slice CT scanners with an inherent temporal resolution range of 75-165 ms. MDCT's and trans-thoracic echocardiograms were retrospectively and independently evaluated by experienced radiologist and cardiologist respectively, for presence of systolic anterior motion of the mitral valve. Results: 7 patients (8.4%) were found to have systolic anterior motion by trans-thoracic echocardiography, from which 6 were found to have systolic anterior motion by ECG-gated cardiac MDCT. Of the 76 patients without systolic anterior motion on trans-thoracic echocardiography, all were correctly identified using ECG-gated cardiac MDCT. The sensitivity, specificity, positive and negative predictive values and accuracy of ECG-gated cardiac MDCT in identifying systolic anterior motion of the mitral valve were 85.7% (6/7), 100% (76/76), 100% (6/6), 98.7% (76/77) and 98.8% (82/83), respectively. Conclusion: ECG-gated cardiac MDCT is comparable to trans-thoracic echocardiography in detecting systolic anterior motion of the mitral valve.

Original languageEnglish (US)
Pages (from-to)69-75
Number of pages7
JournalAcute Cardiac Care
Volume15
Issue number3
DOIs
StatePublished - Sep 1 2013

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Keywords

  • Cardiomyopathy
  • Computed tomography
  • Echocardiography
  • Systolic anterior motion of mitral valve
  • Temporal resolution

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging
  • Emergency Medicine

Cite this

Ghersin, E., Castellon, I., Runco Therrien, J. E., Tanawuttiwat, T., Lessick, J., Checkver, A., & Soto, V. (2013). ECG-gated cardiac MDCT for detection of systolic anterior motion of mitral valve. Acute Cardiac Care, 15(3), 69-75. https://doi.org/10.3109/17482941.2013.822085