Early Stages of Alzheimer's Disease: Evolving the Care Team for Optimal Patient Management

James E. Galvin, Paul Aisen, Jessica B. Langbaum, Eric Rodriguez, Marwan Sabbagh, Richard Stefanacci, Robert A. Stern, Elizabeth A. Vassey, Arno de Wilde, Neva West, Ivana Rubino

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Alzheimer's disease (AD) is a progressive, neurodegenerative disease that creates complex challenges and a significant burden for patients and caregivers. Although underlying pathological changes due to AD may be detected in research studies decades prior to symptom onset, many patients in the early stages of AD remain undiagnosed in clinical practice. Increasing evidence points to the importance of an early and accurate AD diagnosis to optimize outcomes for patients and their families, yet many barriers remain along the diagnostic journey. Through a series of international working group meetings, a diverse group of experts contributed their perspectives to create a blueprint for a patient-centered diagnostic journey for individuals in the early stages of AD and an evolving, transdisciplinary care team. Here, we discuss key learnings, implications, and recommendations.

Original languageEnglish (US)
Article number592302
JournalFrontiers in Neurology
Volume11
DOIs
StatePublished - Jan 22 2021

Keywords

  • Alzheimer's disease
  • dementia
  • diagnosis
  • early detection
  • mild cognitive impairment

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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