Abstract
Early cognitive changes in patients with PD are often subtle and influenced by factors that interact with the disease process, including age and age of disease onset, medication, and the specific constellation of motor symptoms. These factors notwithstanding, there is ample evidence that specific cognitive changes occur early in the course of PD. Whereas language processing deficits are infrequent, subtle changes in olfaction and contrast sensitivity have been repeatedly observed. Executive function deficits are often prominent and, as an integral part of many tasks, also influence performance on a wide range of cognitive measures. This is particularly true for memory and visuospatial dysfunction, two areas that rely heavily on executive demands. Finally, depressive symptoms are also frequent in the early stages of the disease. The significance of early behavioral changes and their prognostic implications are largely unknown and need to be assessed prospectively.
| Original language | English |
|---|---|
| Pages (from-to) | 85-95 |
| Number of pages | 11 |
| Journal | Advances in neurology |
| Volume | 65 |
| State | Published - Jan 1 1995 |
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ASJC Scopus subject areas
- Medicine(all)
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Early cognitive changes and nondementing behavioral abnormalities in Parkinson's disease. / Levin, Bonnie; Katzen, H. L.
In: Advances in neurology, Vol. 65, 01.01.1995, p. 85-95.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Early cognitive changes and nondementing behavioral abnormalities in Parkinson's disease.
AU - Levin, Bonnie
AU - Katzen, H. L.
PY - 1995/1/1
Y1 - 1995/1/1
N2 - Early cognitive changes in patients with PD are often subtle and influenced by factors that interact with the disease process, including age and age of disease onset, medication, and the specific constellation of motor symptoms. These factors notwithstanding, there is ample evidence that specific cognitive changes occur early in the course of PD. Whereas language processing deficits are infrequent, subtle changes in olfaction and contrast sensitivity have been repeatedly observed. Executive function deficits are often prominent and, as an integral part of many tasks, also influence performance on a wide range of cognitive measures. This is particularly true for memory and visuospatial dysfunction, two areas that rely heavily on executive demands. Finally, depressive symptoms are also frequent in the early stages of the disease. The significance of early behavioral changes and their prognostic implications are largely unknown and need to be assessed prospectively.
AB - Early cognitive changes in patients with PD are often subtle and influenced by factors that interact with the disease process, including age and age of disease onset, medication, and the specific constellation of motor symptoms. These factors notwithstanding, there is ample evidence that specific cognitive changes occur early in the course of PD. Whereas language processing deficits are infrequent, subtle changes in olfaction and contrast sensitivity have been repeatedly observed. Executive function deficits are often prominent and, as an integral part of many tasks, also influence performance on a wide range of cognitive measures. This is particularly true for memory and visuospatial dysfunction, two areas that rely heavily on executive demands. Finally, depressive symptoms are also frequent in the early stages of the disease. The significance of early behavioral changes and their prognostic implications are largely unknown and need to be assessed prospectively.
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UR - http://www.scopus.com/inward/citedby.url?scp=0029184154&partnerID=8YFLogxK
M3 - Article
C2 - 7872154
AN - SCOPUS:0029184154
VL - 65
SP - 85
EP - 95
JO - Advances in neurology
JF - Advances in neurology
SN - 0091-3952
ER -