Early and late fistula failure

C. Mercado, Loay Salman, G. Krishnamurthy, K. Choi, S. Artikov, I. Thomas, D. Merrill, A. Asif

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

While an arteriovenous fistula is the best available form of hemodialysis access, a significant number of fistulae never mature to support dialysis (early failure) or fail after successful use (late failure). Venous stenosis and the presence of accessory veins are the two main causes of early failure. Recent data have demonstrated that a great majority of such AVFs can be successfully salvaged by percutaneous interventions and become available for dialysis. In addition to early failure, a great majority of thrombosed fistulae can also be successfully declotted using simple endovascular techniques. Fistula thrombosis has clear differences from graft clotting. First of all, cannulation of a clotted fistula is more challenging. Secondly, thrombus volume present in a clotted fistula can be quite variable. A fistula might thrombose with minimal or no thrombus. At other times, there is moderate-to-severe thrombus burden that accompanies fistula clotting. While percutaneous balloon angioplasty to correct the underlying stenosis might be all that is needed to declot a fistula with no thrombus, thrombo-aspiration is required to successfully declot a fistula with moderate thrombus. Salvage of early and late fistula failure is critical to minimize catheter use and is supported by the National Kidney Foundation Dialysis Outcomes Quality Initiative. Additionally, it is a powerful strategy to maximize AVF use in hemodialysis patients.

Original languageEnglish
Pages (from-to)77-83
Number of pages7
JournalClinical Nephrology
Volume69
Issue number2
StatePublished - Feb 1 2008

Fingerprint

Fistula
Thrombosis
Dialysis
Renal Dialysis
Pathologic Constriction
Endovascular Procedures
Balloon Angioplasty
Arteriovenous Fistula
Catheterization
Veins
Catheters
Transplants
Kidney

Keywords

  • Angioplasty
  • Early arteriovenous fistula failure
  • Fistula thrombectomy
  • Interventional nephrology
  • Vascular access

ASJC Scopus subject areas

  • Nephrology

Cite this

Mercado, C., Salman, L., Krishnamurthy, G., Choi, K., Artikov, S., Thomas, I., ... Asif, A. (2008). Early and late fistula failure. Clinical Nephrology, 69(2), 77-83.

Early and late fistula failure. / Mercado, C.; Salman, Loay; Krishnamurthy, G.; Choi, K.; Artikov, S.; Thomas, I.; Merrill, D.; Asif, A.

In: Clinical Nephrology, Vol. 69, No. 2, 01.02.2008, p. 77-83.

Research output: Contribution to journalArticle

Mercado, C, Salman, L, Krishnamurthy, G, Choi, K, Artikov, S, Thomas, I, Merrill, D & Asif, A 2008, 'Early and late fistula failure', Clinical Nephrology, vol. 69, no. 2, pp. 77-83.
Mercado C, Salman L, Krishnamurthy G, Choi K, Artikov S, Thomas I et al. Early and late fistula failure. Clinical Nephrology. 2008 Feb 1;69(2):77-83.
Mercado, C. ; Salman, Loay ; Krishnamurthy, G. ; Choi, K. ; Artikov, S. ; Thomas, I. ; Merrill, D. ; Asif, A. / Early and late fistula failure. In: Clinical Nephrology. 2008 ; Vol. 69, No. 2. pp. 77-83.
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