Dynamics of crown and lariat ether cation complexation assessed by 13C NMR relaxation times

Luis Echegoyen, Angel Kaifer, H. Durst, Rose Ann Schultz, Dennis M. Dishong, Deepa M. Goli, George W. Gokel

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Abstract

13C NMR longitudinal relaxation times (T1s) have been determined for 15-crown-5, 18-crown-6, and several C-and N-pivot lariat ethers in the absence and presence of Na+, K+, and Ca2+ cations. The C-pivot compounds are 2-substituted 15-crown-5 derivatives as follows, in which Me = CH3 and E = CH2CH2: 1, CH2O-n-Pr; 2, CH2OEOMe; 3, CH2OC6H4-2-OMe; 4, CH2OC6H4-4-OMe. The N-substituted monoaza-15-crown-5 derivatives are as follows: 5, Me; 6, n-Bu; 7, EOMe; 8, EOEOMe. The N-substituted monoaza-18-crown-6 derivatives are as follows: 9, EOMe; 10, EOEOMe. The relaxation time data are used to assess structural changes which accompany cation complexation, the degree of macroring vs. sidearm participation, and the effect of cation charge on the complexation process. In general, the C-pivot lariat ethers (1-4) appear to rely more strongly on the macroring for complexation of cations than do the N-pivot compounds (7-10) except when donor groups are absent from the sidearm (5, 6). For N-pivot lariat ethers 8 and 9, the result of Ca2+ complexation is a rigid, cryptate-like structure in solution, suggesting that Ca2+ plays a very strong organizing role on the ligand structure.

Original languageEnglish
Pages (from-to)5100-5103
Number of pages4
JournalJournal of the American Chemical Society
Volume106
Issue number18
StatePublished - Dec 1 1984
Externally publishedYes

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Crown Ethers
Complexation
Ether
Relaxation time
Ethers
Cations
Positive ions
Nuclear magnetic resonance
Derivatives
Ligands
Carbon-13 Magnetic Resonance Spectroscopy
15-crown-5
18-crown-6

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Echegoyen, L., Kaifer, A., Durst, H., Schultz, R. A., Dishong, D. M., Goli, D. M., & Gokel, G. W. (1984). Dynamics of crown and lariat ether cation complexation assessed by 13C NMR relaxation times. Journal of the American Chemical Society, 106(18), 5100-5103.

Dynamics of crown and lariat ether cation complexation assessed by 13C NMR relaxation times. / Echegoyen, Luis; Kaifer, Angel; Durst, H.; Schultz, Rose Ann; Dishong, Dennis M.; Goli, Deepa M.; Gokel, George W.

In: Journal of the American Chemical Society, Vol. 106, No. 18, 01.12.1984, p. 5100-5103.

Research output: Contribution to journalArticle

Echegoyen, L, Kaifer, A, Durst, H, Schultz, RA, Dishong, DM, Goli, DM & Gokel, GW 1984, 'Dynamics of crown and lariat ether cation complexation assessed by 13C NMR relaxation times', Journal of the American Chemical Society, vol. 106, no. 18, pp. 5100-5103.
Echegoyen L, Kaifer A, Durst H, Schultz RA, Dishong DM, Goli DM et al. Dynamics of crown and lariat ether cation complexation assessed by 13C NMR relaxation times. Journal of the American Chemical Society. 1984 Dec 1;106(18):5100-5103.
Echegoyen, Luis ; Kaifer, Angel ; Durst, H. ; Schultz, Rose Ann ; Dishong, Dennis M. ; Goli, Deepa M. ; Gokel, George W. / Dynamics of crown and lariat ether cation complexation assessed by 13C NMR relaxation times. In: Journal of the American Chemical Society. 1984 ; Vol. 106, No. 18. pp. 5100-5103.
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